English 
Español 
français 
العربية Search
Search
Chlortetracycline hydrochloride is a broad-spectrum antibiotic that has antibacterial effects on both gram-positive and gram-negative bacteria.
Chlortetracycline hydrochloride is mainly used for the treatment of conjunctivitis, veterinary drugs are used in feed addition or animal diseases, suitable for chicken white diarrhea, typhoid fever, porcine bacterial enteritis and poultry and livestock bacterial diseases such as paratyphoid fever, cholera, etc.
Items | Specifications | Results |
Characters | Yellow powder.Slightly soluble in water and in ethanol(96%).It dissolves in solutions of alkali hydroxides and carbonates. | Complies |
Identification C | It gives reaction (a) of chlorides. | Complies |
Identification D | The principal peak in the chromatogram obtained with the test solution is similar in retention time to the principal peak in the chromatogram obtained with reference solution(a). | Complies |
pH | 2.3 to 3.3(10mg/ml) | 2.6 |
Specific optical rotation | -235°to -250°(2.5mg/ml) | -246° |
Absorbance | Not more than 0.40(5mg/ml,460nm) | 0.16 |
Related substances Impurity a(4-Ectc) Impurity B(demeclocycline) Impurity E | Not more than 4.0% Not more than 1.0% Not more than 1.0% | 1.61% 0.11% 0.19% |
Impurityl(Anhydrochlortetracycline) | Not more than 0.2% | 0.08% |
Conclusion | The product conforms to the above specifications. | |
| Product parameters | |
| Cas number: | 64-72-2 |
| Appearance: | Yellow powder |
| Purity: | 94.5~102.0% |
| Package details: | 1kg/foil bag; 25kg/drum |
| Brand: | Fortunachem |
Chlortetracycline Hydrochloride is the hydrochloride salt form of chlortetracycline, a broad-spectrum tetracycline antibiotic originally derived from Streptomyces aureofaciens. It was the first tetracycline discovered.
Veterinary Medicine (Major Use):
Feed Additive: Widely used in livestock (poultry, swine, cattle) for growth promotion, disease prevention, and treatment of bacterial infections (e.g., respiratory diseases, anaplasmosis).
Topical Applications: Used in ointments for eye and skin infections in animals.
Human Medicine (Historically & Niche):
Historically treated various bacterial infections (respiratory, urinary, acne). Now largely obsolete in human therapy due to resistance, side effects, and the development of better tetracyclines (e.g., doxycycline).
May have very limited use for specific sensitive organisms.
Agriculture & Apiculture:
Used to control bacterial diseases in plants (e.g., fire blight) and in beehives for American Foulbrood (though regulations are strict).
Biochemical Research:
Used in laboratories as a protein synthesis inhibitor (binds to the 30S ribosomal subunit) to study bacterial and cellular functions.
Mechanism: Inhibits bacterial protein synthesis.
Form: The hydrochloride salt improves water solubility and stability for formulation.
Restrictions: Its use in food-producing animals is heavily regulated in many countries (with mandatory withdrawal periods before slaughter) to limit antibiotic resistance and residues in the food chain.
In summary, chlortetracycline HCl is now primarily a veterinary antibiotic and growth promoter, with very limited and declining use in human medicine due to advancements and resistance concerns.
Fortunachem Provides Not Only Professional Chemical Products But Also Professional Help
Keeping you up-to-date with all the latest information, news, and events about Fortunachem!
Quick Links
Add:
E-mail:
