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Specifications of 3-Methylanthranilic acid CAS 4389-45-1 COA:
Items | Specifications | Results |
Appearance | White Crystal Powder | Accordant |
Purity(HPLC)% | ≥99.0% | 99.8 |
Water content, % | ≤0.5 | 0.3 |
Melting range ℃ | 172-176 | 172.8-173.4 |
Conclusion | The product conforms to the above specifications. | |
Product Name:3-Methylanthranilic acid
CAS:4389-45-1
MF:C8H9NO2
Melting point :172.8-173.4
form:powder
color:White Crystal
Uses:
2-Amino-3-Methylbenzoic Acid (CAS: 4389-45-1), also known as 3-Methylanthranilic Acid, is an aromatic amino acid featuring a benzene ring with an amino group (–NH₂) at the 2-position, a methyl group (–CH₃) at the 3-position, and a carboxylic acid (–COOH) at the 1-position. It appears as a white to pale yellow crystalline powder with a molecular weight of 151.16 g/mol, melting point of 173–177 °C, and amphoteric character due to its dual functional groups. Commercially available at ≥98% purity, it is soluble in ethanol, methanol, DMSO, and DMF, and stable at room temperature when stored sealed and away from light.
Key Uses
Pharmaceutical Intermediates: A critical building block for synthesizing ropivacaine, a widely used long-acting local anesthetic preferred over bupivacaine for its lower cardiotoxicity. It is also a known metabolite of lidocaine, making it relevant in pharmacokinetic research, and serves as a precursor for NSAIDs, anticonvulsants, and non-natural amino acids in peptide synthesis.
Agrochemical Intermediates (Primary Commercial Driver): This is the compound's most commercially significant application. It is a key intermediate for chlorantraniliprole, one of the world's best-selling insecticides (annual sales exceeding $1 billion). Specifically, it is used to prepare K-amine (2-amino-5-chloro-N,3-dimethylbenzamide), a critical precursor. The global market for this compound was valued at approximately ¥1.6 billion in 2024, with a projected CAGR of 3.7% through 2031. It also serves in synthesizing metabolites of the fungicide Metalaxyl.
Dye Chemistry: The amino group enables diazotization and coupling reactions to produce azo dyes for textiles, leather, and paper coloring.
Research & Analytical: Used in chiral ligand development, metal ion detection, and as a versatile scaffold for novel compound synthesis.
Selling Points
Dual reactive sites — ortho-arranged –NH₂ and –COOH allow selective amidation, esterification, diazotization, and alkylation, enabling highly versatile multi-step synthesis.
Tied to a blockbuster agrochemical — demand is directly linked to chlorantraniliprole production, ensuring strong, sustained industrial demand.
Pharmaceutical relevance — essential for ropivacaine synthesis and lidocaine metabolism studies, providing diversified demand across healthcare.
High purity & quality assurance — available at ≥98% with batch-specific COAs (loss on drying ≤0.5%, heavy metals ≤10 ppm, NMR/LC-MS confirmed).
Cost-effective & scalable — multiple established synthesis routes (catalytic hydrogenation, iron powder reduction, ammonolysis) ensure reliable supply from gram to 500 kg scale.
Stable & easy to handle — chemically stable at room temperature; standard PPE sufficient for handling.
Three-industry diversification — serves pharmaceuticals, agrochemicals, and dyes simultaneously, reducing supply-chain risk.
Global supply chain — supplied by TCI, AbMole, Benchchem, and numerous Chinese manufacturers, ensuring competitive pricing and availability.
In summary, 2-Amino-3-Methylbenzoic Acid is a high-value, versatile intermediate whose commercial importance is anchored by its indispensable role in chlorantraniliprole and ropivacaine synthesis, offering excellent performance, reliability, and cost-effectiveness across multiple industries.
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FAQ From Wuhan Fortuna Chemical Co.,Ltd
Q1: Can I get a sample for free ?
A: For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test.
Q2: How to confirm the product quality before placing orders ?
A: Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order.
Q3: What is the payment you accept?
A: For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us.
Q4: What is your shipment way ?
A: For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement.
Q5: How long is your after-sales service?
A: We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company.
Q6: How do you treat quality complaint ?
A: We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers.
Name:Wuhan Fortuna Chemical Co.,Ltd
Category:Others
Trade Category: Trading Company
Employees: 11 - 50 People
Address: Room 2015, No.2 Building, Kaixin Mansion No.107
Company Information: Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide 3-Methylanthranilic acid with good quality and best price, welcome to contact us to get COA/TDS/MSDS of 3-Methylanthranilic acid.
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