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Glucosyl Fluoride (typically α -D-Glucopyranosyl Fluoride, CAS: 2106-10-7) is a specialized organofluorine compound where the anomeric hydroxyl group of glucose is replaced by a fluorine atom.
Its primary selling points revolve around its unique chemical properties:
Superior Glycosyl Donor: As its most valuable application, it is essential in synthesizing complex oligosaccharides and glycoproteins. The highly stable carbon-fluorine (C-F) bond offers excellent shelf stability, yet it can be selectively activated by specific catalysts (like silver salts) to achieve high stereoselectivity in difficult chemical couplings.
Versatile Intermediate: It serves as a crucial building block in pharmaceutical research and the creation of biochemical probes.
High-Purity Reagent: Commercially available with purities exceeding 95-98%, it is strictly marketed as a high-quality reagent for scientific research and organic synthesis, not for human use.
It typically refers to α -D-Glucopyranosyl Fluoride (CAS No. 2106-10-7).
Chemically, it is a product where the hydroxyl group (-OH) at the anomeric carbon (C1 position) of a glucose molecule is substituted by a fluorine atom (-F).
Molecular Formula: C₆H₁₁FO₅
Molecular Weight: Approx. 182.15
Appearance: Usually a white powder or off-white solid
Storage: Typically requires storage under low temperature (e.g., -20℃ or 2-8℃), dry, and light-protected conditions.
Key Selling Points (Main Value & Applications)
The primary "selling points" of Glucosyl Fluoride center on its unique chemical properties as a research reagent and pharmaceutical intermediate:
1. Excellent Glycosyl Donor (Core Application)
This is its greatest value. It is widely used as a "glycosyl donor" in the synthesis of complex oligosaccharides, polysaccharides, and glycoproteins.
Unique Stability & Reactivity: Due to the extremely high bond energy of the carbon-fluorine (C-F) bond, glycosyl fluorides are generally very stable. However, they can be efficiently activated by specific activators (such as silver salts or Lewis acids) to undergo glycosylation reactions.
High Selectivity: In the synthesis of macromolecules (e.g., 151-mer mannan polysaccharides) or complex natural products (like avermectin), glycosyl fluorides can achieve extremely high stereoselectivity, accomplishing module couplings that are difficult for other glycosylating agents.
2. Important Pharmaceutical & Biochemical Intermediate
It serves as a key building block for synthesizing various complex natural products and drugs.
It is commonly used to prepare aryl glycosides, playing a vital role in drug discovery and the construction of biochemical probes.
3. Research-Grade Attribute
The vast majority of Glucosyl Fluoride sold on the market is explicitly labeled "For research use only, not for human or veterinary diagnostic or therapeutic use."
With purities typically ranging from 95% to over 98%, it serves as a high-purity foundational reagent in the fields of biomedicine and organic synthesis.
Additional Note
Besides the most common α -D configuration (CAS: 2106-10-7), its stereoisomer
β -D-Glucopyranosyl Fluoride (CAS: 7617-95-0) also exists. The two have different physical properties (such as melting points) and chemical reactivities.
If you are looking for purchasing channels, numerous biotech companies (both domestic and international) offer various specifications (ranging from milligram to kilogram scales) in stock.
Also, if you have any other questions, you can contact us
FAQ From Wuhan Fortuna Chemical Co.,Ltd
Q1: Can I get a sample for free ?
A: For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test.
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A: We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers.
Name:Wuhan Fortuna Chemical Co.,Ltd
Category:Others
Trade Category: Trading Company
Employees: 11 - 50 People
Address: Room 2015, No.2 Building, Kaixin Mansion No.107
Company Information: Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Azaperone with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Azaperone.
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