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Introduction of 2-Mercaptopyridine (C₅H₅NS) is an organosulfur compound with a pyridine ring and a thiol (-SH) group at the 2-position. A yellow crystalline solid with a sulfurous odor, it is soluble in organic solvents but poorly in water. Its weakly acidic thiol (pKa ~4.5–5) enables metal coordination, forming stable complexes with transition metals (e.g., Cu, Ni), making it valuable in catalysis and material science. Used as a ligand, synthetic intermediate in pharmaceuticals, and biochemical protein modifier. Toxic and irritant, it requires careful handling (gloves, ventilation). Distinct from 4-mercaptopyridine and its sodium salt (enhanced solubility). Avoid confusion with antifungal 2-mercaptopyridine N-oxide.
Description of 2-Mercaptopyridine from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of 2-Mercaptopyridine | |
Product Name | 2-Mercaptopyridine |
CAS NO. | 73018-10-7 |
Apperance | Light yellow to yellow crystalline powder |
Assay | 99.32% |
Pacakge | 1kg/Foil Bag, 25kg/ Box/carton |
MOQ | 1kg |
Storage | |
Shelf Life | 2 Years |
Brand | Fortunachem |
Specifications(COA) of 2-Mercaptopyridine CAS 73018-10-7
Items | Specifications | Results |
Appearance | Light yellow to yellow crystalline powder | Conforms |
Identifacation | Conforms | Conforms |
Loss on drying | ≤1.0% | 0.12% |
Purity | ≥99.0% | 99.32% |
Conclusion | The results conform to the Enterpris Standard | |
Introduction of 2-Mercaptopyridine (C₅H₅NS) is an organosulfur compound with a pyridine ring and a thiol (-SH) group at the 2-position. A yellow crystalline solid with a sulfurous odor, it is soluble in organic solvents but poorly in water. Its weakly acidic thiol (pKa ~4.5–5) enables metal coordination, forming stable complexes with transition metals (e.g., Cu, Ni), making it valuable in catalysis and material science. Used as a ligand, synthetic intermediate in pharmaceuticals, and biochemical protein modifier. Toxic and irritant, it requires careful handling (gloves, ventilation). Distinct from 4-mercaptopyridine and its sodium salt (enhanced solubility). Avoid confusion with antifungal 2-mercaptopyridine N-oxide.
Application of Here's a detailed overview of 2-Mercaptopyridine:
Organosulfur compound with a pyridine ring and a thiol (-SH) group at the 2-position.
Chemical Formula: C5H5NSC5H5NS.
CAS Number: 2637-34-5.
Other Names: 2-Pyridinethiol, 2-Thiopyridine.
1. Physical State:
Yellow to off-white crystalline solid.
Distinctive sulfur-like odor (common for thiols).
2. Solubility:
Soluble in organic solvents (ethanol, DMSO, chloroform).
Poor solubility in water.
3. Acidity:
Weakly acidic (pKa ~4.5–5.0 for the thiol group).
4. Reactivity:
Forms stable metal complexes (via S and N donor atoms).
Undergoes oxidation to disulfides or alkylation reactions.
1. Coordination Chemistry:
Ligand for transition metals (e.g., Cu, Ni, Co) in catalysis or material science.
Used to synthesize metal-organic frameworks (MOFs) or catalysts.
2. Organic Synthesis:
Building block for pharmaceuticals (e.g., antiviral or anticancer agents).
Intermediate in the synthesis of heterocyclic compounds.
3. Analytical Chemistry:
Chelating agent for metal ion detection or extraction.
4. Biochemistry:
Modifies proteins/enzymes by reacting with cysteine residues.
Hazards:
Toxic if ingested/inhaled.
Causes skin/eye irritation.
Releases toxic fumes (e.g., SOx) upon combustion.
Precautions:
Use gloves, goggles, and fume hood.
Store in a cool, dry place away from oxidizers.
Disposal: Treat as hazardous waste.
Its sodium salt (2-mercaptopyridine sodium salt) is more water-soluble and used in biochemical assays.
Contrast with 4-mercaptopyridine (thiol at the 4-position), which has different coordination behavior.
Avoid confusion with 2-mercaptopyridine N-oxide (a distinct antifungal/antibacterial agent).
Let me know if you need synthesis pathways or specific reaction examples!
FAQ From Wuhan Fortuna Chemical Co.,Ltd | |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
How do you treat quality complaint ? | |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide 2-Mercaptopyridine with good quality and best price, welcome to contact us to get COA/TDS/MSDS of 2-Mercaptopyridine.
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