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Atomoxetine hydrochloride is a non-stimulant medication primarily used to treat Attention-Deficit/Hyperactivity Disorder (ADHD) in children, adolescents, and adults.
Its main selling points include:
No Addiction Risk: As a non-stimulant, it lacks the abuse potential of traditional ADHD drugs, making it safer for long-term use.
24-Hour Symptom Control: Taken once or twice daily, it provides all-day symptom management and prevents evening "rebound" effects.
Mood Benefits: It can help alleviate comorbid anxiety or depression in ADHD patients.
However, it has a slower onset of action, typically requiring 2 to 4 weeks to show significant effects. Common side effects may include nausea, decreased appetite, and fatigue.
Specifications of Atomoxetine hydrochloride CAS 82248-59-7 COA:
Items | Specifications | Results |
Appearance | White or almost white powder | White powder |
Solubleness | Soluble in anhydrous ethanol,sparingly soluble in water,practically insoluble in n-heptane. | Complied |
Identification | IR：The IR absorption spectrum complied with that of the reference substance. | Complied |
HPLC:The retention time of principal peak in test solution should comply with retention time of principal peak in system suitability solution,as obtained in isomers. | Complied | |
Chloride | Positive reaction | Positive |
Specific rotation | -38°~-45° | -40° |
Loss On Drying | NMT 0.5% | 0.06% |
Residue on ignition | NMT 0.1% | 0.04% |
Heavy metals | NMT 10ppm | Less than 10ppm |
Related substances | Impurity A(RRT≈0.7)：NMT 0.3% | 0.01% |
Any unspecified impurities:NMT 0.10% | Not detected | |
Total impurities:NMT 0.5% | 0.01% | |
Isomers | Impurity B(RRT≈0.5):NMT 0.5% | 0.02% |
Impurity D(RRT≈0.6):NMT 0.1% | 0.01% | |
Other impurities:NMT 0.1% | Not Detected | |
Residual solvents | Methanol:NMT 0.3% | Not Detected |
Acetonitrile:NMT 0.041% | 0.016% | |
Toluene:NMT 0.089% | Not detected | |
Assay | 98.0%~102.0%(dried substance) | 99.6% |
Conclusion | The product conforms to the above specifications. | |
Product Name:Atomoxetine hydrochloride
CAS:82248-59-7
MF:C17H22ClNO
Melting point :167-169°C
form:powder
color:White or almost white
Uses:
Atomoxetine Hydrochloride is a selective norepinephrine reuptake inhibitor (SNRI). It is primarily used to treat Attention-Deficit/Hyperactivity Disorder (ADHD) and is currently the only non-central nervous system (non-stimulant) medication approved by the FDA for this condition.
Primary Uses of the Medication
Core Indication: It is mainly used to treat ADHD in children, adolescents, and adults. It effectively improves symptoms of inattention, hyperactivity, and impulsivity.
Other Potential Uses: Research indicates that it can increase neurotransmitter levels in the prefrontal cortex, making it potentially beneficial for treating excessive daytime sleepiness and cataplexy caused by narcolepsy.
Key Selling Points & Clinical Advantages
Compared to traditional ADHD medications, Atomoxetine Hydrochloride offers several distinct advantages in clinical practice:
Non-Stimulant with No Addiction Risk: This is its biggest highlight. Traditional ADHD drugs (like methylphenidate) are central nervous system stimulants that carry a risk of abuse and addiction, and are therefore strictly regulated. Atomoxetine is not a stimulant, has no addictive potential, and is safer for patients at risk of substance dependence or those requiring long-term treatment.
24-Hour Symptom Control: Atomoxetine is rapidly absorbed orally and only needs to be taken once or twice a day. It provides all-day symptom control, benefiting both daytime learning/work and evening behavior. It avoids the "rebound" effect often seen with traditional stimulants when the medication wears off after school or on weekends.
Benefits for Comorbid Depression/Anxiety: While enhancing norepinephrine function, Atomoxetine also helps alleviate accompanying depressive or anxious moods in some patients, making it suitable for ADHD patients with co-occurring emotional issues.
Favorable Cardiovascular Profile: Clinical data shows that Atomoxetine does not increase the incidence of cardiovascular events associated with methylphenidate, making it relatively friendly for patients with mild cardiovascular concerns (though caution is still required for those with severe cardiovascular disease).
Limitations to Note
Despite its advantages, Atomoxetine has a relatively slow onset of action; it typically takes 2 to 4 weeks or more of continuous use to see significant improvements. Additionally, it may cause side effects such as nausea, decreased appetite, fatigue, and dizziness. In rare cases, it may carry a risk of hepatotoxicity or cause increases in blood pressure and heart rate.
Also, if you have any other questions, you can contact us
FAQ From Wuhan Fortuna Chemical Co.,Ltd
Q1: Can I get a sample for free ?
A: For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test.
Q2: How to confirm the product quality before placing orders ?
A: Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order.
Q3: What is the payment you accept?
A: For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us.
Q4: What is your shipment way ?
A: For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement.
Q5: How long is your after-sales service?
A: We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company.
Q6: How do you treat quality complaint ?
A: We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers.
Name:Wuhan Fortuna Chemical Co.,Ltd
Category:Others
Trade Category: Trading Company
Employees: 11 - 50 People
Address: Room 2015, No.2 Building, Kaixin Mansion No.107
Company Information: Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Atomoxetine hydrochloride with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Atomoxetine hydrochloride.
1. Guaranteed purity;
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