Name: Manufacturer Supply Best Price Bulk Price Sodium 4-aminosalicylate dihydrate CAS 6018-19-5 with good service
Brand: Wuhan Fortuna Chemical Co., Ltd.

Items	Specifications	Results
Appearance	Off-white or slightly yellowish powder	Conforms
Identification	react positive	Conforms
The color and clarity of the solution	comply with the regulations	Conforms
M-aminophenol	≤0.05%	Conforms
Loss on Drying	16.0-17.5%	16.8%
PH	6.5-8.5	7.41
heavy metal content	≤10ppm	Conforms
ferric salt	≤15ppm	Conforms
chloride	≤0.005%	Conforms
sulfate	≤0.05%	Conforms
Content	≥99.0%	99.40%
Conclusion	The product conforms to the above specifications.

Sodium 4-aminosalicylate dihydrate (CAS No. 6018-19-5; anhydrous form CAS 133-10-8) is the sodium salt of 4-aminosalicylic acid (PAS), stabilized with two molecules of water.

Chemical Nature: It is a white to off-white crystalline powder, highly soluble in water. The dihydrate form offers enhanced stability compared to the anhydrous salt, preventing rapid oxidation of the sensitive amino group.

Primary Applications:

Anti-Tuberculosis Agent: Historically and currently used as a second-line antibiotic for treating multidrug-resistant tuberculosis (MDR-TB), inhibiting bacterial folate synthesis.

Anti-inflammatory: Used in the treatment of inflammatory bowel diseases (e.g., ulcerative colitis) in some regions.

Pharmaceutical Intermediate: A key starting material for synthesizing related salicylate derivatives and mesalazine impurities.

Key Selling Points

Targeted at pharmaceutical manufacturers, generic drug developers, and research institutions:

Superior Stability (Dihydrate Form):

The dihydrate crystal lattice provides excellent protection against oxidation and discoloration (a common issue with aminosalicylates), ensuring a longer shelf life and consistent potency during storage and transport.

High Purity & Low Impurity Profile:

Manufactured with strict control over critical impurities (e.g., 3-amino isomer, salicylic acid, heavy metals), meeting stringent pharmacopoeial standards (USP, EP, ChP). Essential for passing regulatory audits for MDR-TB drug formulations.

Regulatory Compliance & Documentation:

Supplied with comprehensive DMF (Drug Master File) support, Certificates of Analysis (COA), and full traceability. Ideal for companies filing ANDAs or seeking WHO prequalification for tuberculosis treatments.

Optimized Solubility for Formulation:

The sodium salt form offers high aqueous solubility, facilitating the development of various dosage forms including oral granules, tablets, and even intravenous solutions required for severe TB cases.

Scalable GMP Production:

Produced in GMP-certified facilities with capacity for metric-ton scale supply, ensuring reliable sourcing for global health programs and large-scale generic manufacturing.

Important Notice: This product is sold strictly as a pharmaceutical raw material or research chemical for legal manufacturing and laboratory use. It is not a finished dosage form for direct human consumption without further processing and regulatory approval.