5-Fluorouracil has an effect on all stages of the proliferative stage, can prevent the formation of thymine, inhibit DNA biosynthesis, and thus inhibit the growth of cancer cells. 5-Fluorouracil is first converted to 5-fluoro-2-deoxyuracil nucleotide in vivo, inhibits thymine nucleotide synthetase, blocks the conversion of uracil deoxynucleotide to thymine deoxynucleotide, thereby affecting DNA biosynthesis. At the same time, it can incorporate RNA, and directly inhibit RNA synthesis by blocking the incorporation of uracil and orotic acid into RNA.
5-Fluorouracil is used in the treatment of digestive system cancer, head and neck cancer, gynecological cancer, lung cancer, liver cancer, bladder cancer and skin cancer.
|Appearance||White crystalline powder||Conforms|
|Loss on drying||≤0.50%||0.03%|
|Appearance:||White crystalline powder|
|Package details:||1kg/foil bag; 25kg/drum|
Antineoplastic, pyrimidine antimetabolite.
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