Terlipressin is mainly used to treat acute varicose vein rupture and bleeding.
The pharmacological effect of terlipressin is to contract the smooth muscle of splanchnic blood vessels, reduce splanchnic blood flow (such as reducing blood flow in the mesentery, spleen, uterus, etc.), thereby reducing portal blood flow, reducing portal vein pressure, on the other hand, it can also reduce the effect of plasma renin concentration, thereby increasing renal blood flow in patients with hepatorenal syndrome, improving renal function, and increasing urine output.
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