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Introduction of Isometheptene Mucate is a vasoconstrictor and mild stimulant used to treat migraines and tension headaches. It works by narrowing dilated blood vessels in the brain, reducing pain. Typically combined with acetaminophen (pain reliever) and dichloralphenazone (sedative), it was sold under brands like Midrin (now discontinued in the U.S.). Side effects may include dizziness, increased heart rate, and nausea. Due to its sympathomimetic effects, it’s unsafe for those with hypertension, heart disease, or glaucoma. While once common, it has been largely replaced by newer migraine drugs like triptans. Check local availability and consult a doctor before use.
Description of Isometheptene mucate from Wuhan Fortuna Chemical Co.,Ltd
Basic Information of Isometheptene mucate | |
Product Name | |
CAS NO. | |
Apperance | White crystall powder |
Assay | 99.2% |
Pacakge | 1kg/Foil Bag, 25kg/ Box/carton |
MOQ | 1kg |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Fortunachem |
Specifications(COA) of Isometheptene mucate CAS 7492-31-1
ITEMS | SPECIFICATIONS | RESULTS |
Appearance | ||
Water | ≤0.5% | 0.27% |
Assay | ≥98% | 99.2% |
Conclusion | Complies With Specification | |
Introduction of Isometheptene Mucate is a vasoconstrictor and mild stimulant used to treat migraines and tension headaches. It works by narrowing dilated blood vessels in the brain, reducing pain. Typically combined with acetaminophen (pain reliever) and dichloralphenazone (sedative), it was sold under brands like Midrin (now discontinued in the U.S.). Side effects may include dizziness, increased heart rate, and nausea. Due to its sympathomimetic effects, it’s unsafe for those with hypertension, heart disease, or glaucoma. While once common, it has been largely replaced by newer migraine drugs like triptans. Check local availability and consult a doctor before use.
Application of Isometheptene Mucate is a combination medication primarily used to treat tension headaches and migraine attacks. Here’s a detailed breakdown:
Isometheptene – A sympathomimetic amine that acts as a vasoconstrictor, narrowing dilated blood vessels in the brain (a key factor in migraines).
Mucate – A salt form (mucic acid derivative) that enhances solubility and absorption.
Vasoconstriction: Isometheptene reduces excessive blood vessel dilation in the brain, which helps relieve migraine-related pain.
Mild Stimulant Effect: It may also have slight central nervous system (CNS) effects, potentially counteracting migraine-associated lethargy.
Midrin (formerly available in the U.S., now discontinued)
Duradrin (alternative formulation)
Other regional brand names may exist.
Each capsule usually contains:
Isometheptene mucate (65 mg)
Dichloralphenazone (a mild sedative, 100 mg)
Acetaminophen (paracetamol, 325 mg) – for pain relief.
Primarily used for acute migraine and tension-type headaches.
Works best when taken at the earliest signs of a migraine.
Not intended for prophylactic (preventive) use.
Due to its sympathomimetic properties, possible side effects include:
Dizziness, drowsiness (from dichloralphenazone)
Nausea, nervousness
Increased heart rate or blood pressure (caution in hypertensive patients)
Discontinued in the U.S. (Midrin was withdrawn due to regulatory issues, not safety concerns).
Still available in some countries (e.g., Mexico, Canada under different brand names).
Alternatives: Triptans (e.g., sumatriptan), NSAIDs, or newer migraine-specific drugs (gepants, ditans).
Not safe for people with heart disease, severe hypertension, or glaucoma (due to vasoconstriction risk).
Avoid with MAO inhibitors (risk of hypertensive crisis).
Limited evidence: Some studies question its efficacy compared to modern migraine treatments.
FAQ From Wuhan Fortuna Chemical Co.,Ltd | |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
How do you treat quality complaint ? | |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Isometheptene mucate with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Isometheptene mucate.
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