Colistin sulfate is mainly used for sensitive bacterial infections, such as sepsis, acute enteritis, urinary tract infections, etc.
Colistin sulfate has a strong antibacterial effect on Escherichia coli, Salmonella, Pasteurella, dysentery bacillus, Brucella, Vibrio, Pseudomonas aeruginosa and other gram-negative bacteria, of which the bactericidal effect on Pseudomonas aeruginosa and Vibrio is strong, the bactericidal mechanism of colistin sulfate is to damage the bacterial cell membrane, increase its permeability, so that the leakage of amino acids, purines, pyrimidine, K+ and so on in the bacteria can also affect the function of nucleoplasm and ribosomes, resulting in bacterial death.
|Appearance||White or almost, hygroscopic powder||Conforms|
|Loss on drying||≤3.5%||2.3%|
|Assay(Dried substance)||≥19000 IU/mg||23132 IU/mg|
|Appearance:||White or almost, hygroscopic powder|
|Purity:||19000 IU/mg min|
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