Perindopril erbumine is used to treat conditions such as hypertension and congestive heart failure.
Perindopril erbumine is an inhibitor of an enzyme that converts angiotensin I to angiotensin II (angiotensin-converting enzyme). This invertase or kinase is a peptide chain terminal lyase that converts angiotensin I into angiotensin Il, which constricts blood vessels, and it also degrades bradykinin, which relaxes blood vessels, into inactive heptapeptides. Inhibition of angiotensin-converting enzyme leads to a decrease in angiotensin II in plasma, which can lead to increased plasma renin activity (by inhibiting negative feedback of renin release) and reduce aldosterone secretion. Because angiotensin-converting enzyme inactivates bradykinin, angiotense inversion inhibition also increases the activity of the circulating and local kallikrein-kallin system (and thus the prostaglandin system).
|Appearance||White or almost white crystalline powder, slightly hygroscopic||Conforms|
|Impurity A (TLC)||≤ 0.25%||Conforms|
|Stereochemical purity||Impurity I: ≤0.1%||0.08%|
|Any impurity ≤0.1%||Not detected|
|Assay (By titrimetry)||99.0%~101.0% (on anhydrous basis)||99.6%|
|Appearance:||Off-white to white crystalline powder|
|Package details:||1kg/foil bag; 25kg/drum|
Used for the treatment of high blood pressure, congestive heart failure and other diseases.
Fortunachem Provides Not Only Professional Chemical Products But Also Professional Help
Keeping you up-to-date with all the latest information, news, and events about Fortunachem!