Nisoldipine is used to treat hypertension, heart failure, ischemic heart disease, angina and so on.
Nisoldipine has a high degree of selectivity for vascular smooth muscle, and the activity of blood vessels is 3~5 times that of other tissues, which can significantly reduce peripheral vascular resistance and myocardial oxygen consumption, increase coronary blood flow, improve ischemic perfusion, improve myocardial tolerance to ischemia, and significantly reduce the proportion of necrotic part of myocardial hypoperfusion area after coronary artery occlusion, while expanding peripheral arteries, reducing peripheral resistance and cardiac afterload, increasing cardiac output and cardiac index, relieving coronary spasm, and improving left ventricular function. Prevents fatal ventricular fibrillation with pronounced, long-lasting antihypertensive effects.
|Appearance||Yellow crystalline powder||Conforms|
|Loss on drying||≤0.5%||0.2%|
|Residue on ignition||≤0.1%||0.06%|
|Appearance:||Yellow crystalline powder|
|Package details:||1kg/foil bag; 25kg/fiber drum|
Dihydropyridine calcium channel blocker, antihypertensive and antianginal.
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