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Mycophenolic acid is used for the treatment of cardiac and renal transplant rejection and immune diseases such as lupus nephritis, vasculitis, etc.
Mycophenolic acid is a potent noncompetitive hypoxanthine nucleotide dehydrogenase (IMPDH) inhibitor that selectively inhibits lymphocyte proliferation, T and B lymphocytes stimulation caused by mitogen and allogeneic antigens, and inhibits B lymphocyte production of antibodies. In addition, mycophenolic acid can also block the migration of lymphocytes and monocytes to the site of rejection and inflammation by inhibiting the glycosylation of lymphocytes and monocytes surface adhesion molecules related to endothelial cell adhesion; Therefore, mycophenolic acid has good antiviral, antifungal, antibacterial, antitumor and immunosuppressive activities.
Items | Specification | Result |
Assay | 97%~103% | 100.5% |
Appearance | White or off-white crystalline powder | White crystalline powder |
| Loss on drying | ≤0.5% | 0.07% |
| Heavy metals | ≤20ppm | <20ppm |
| Residue on ignition | ≤0.1% | 0.02% |
| Relative substance | Total impurities≤1.0% Max single impurity≤0.5% | 0.4% 0.08% |
| Product parameters | |
| Cas number: | 24280-93-1 |
| Appearance: | White or off-white crystalline powder |
| Purity: | 97%-103% |
| Package details: | 1kg/foil bag;25kg/drum |
| Brand: | Fortunachem |
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