Milbemycin oxime is a broad-spectrum antiparasitic drug with an active effect on worms and mites. Milbemycin oxime is a semi-synthetic macrocyclic lactone prepared by the oxidation and oximation of a mixture of two natural products, milbemycin A3 and A4 (in ~30:70 ratio). Milbemycin oxime is used therapeutically for the prevention of intestinal parasites in dogs. Like the other milbemycin/avermectins, it was developed for intestinal parasite control in animals and acts by opening glutamate sensitive chloride channels in neurons of invertebrates leading to paralysis by hyperpolarisation of these cells and signal transfer blocking.
|Appearance||White to light yellow amorphous powder||White powder|
|Residue on ignition||≤0.5%||0.1%|
|Assay||Milbemycin Oxime (A3+A4): 95.0%~102.0%||98.1%|
|Ratio of Milbemycin A4 Oxime ≥0.75||0.94|
|Ratio of Milbemycin A3 Oxime ≤0.25||0.06|
|Appearance:||White to off white powder|
|Package details:||10g/bottle; 100g/foil bag|
Milbemycin oxime is used for intestinal parasite control in animals.
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