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Irinotecan hydrochloride can be used in the treatment of colon and rectal cancer.
Irinotecan hydrochloride has been used: 1. in combination with 5-fluorouracil for screening growth inhibitory functionality in MDA-MB-231 breast cancer cells. 2. in chemosensitivity screening of high-grade appendiceal (HGA) and low-grade appendiceal (LGA) organoids. 3. as a chemotherapeutic agent in the cytotoxicity studies in combination with heat shock proteins inhibitors (HPSC1) in HT29 colon cancer cells.
| Items | Specification | Result |
Assay | ≥99% | 99.9% |
Appearance | Yellowish or yellow crystalline powder | Conforms |
| Heavy metals | ≤20ppm | Conforms |
| Residue on ignition | ≤0.1% | Conforms |
| Total impurities | ≤1.0% | 0.1% |
| Single impurity | ≤0.3% | Conforms |
| Methylene dichloride | ≤0.06% | ND |
| chloroform | ≤0.006% | Conforms |
| Product parameters | |
| Cas number: | 100286-90-6 |
| Appearance: | Yellowish or yellow crystalline powder |
| Purity: | 99%min |
| Package details: | 10g,100g,1kg/foil bag;25kg/drum |
| Brand: | Fortunachem |
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