Dolutegravir sodium is used to treat AIDS. Dolutegravir sodium is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir sodium is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir sodium has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
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