Pemetrexed disodium is a multi-target antifolate preparation structurally containing pyrropyrimidine group at its core, which is a dual inhibitor of nucleotide synthase/dihydrofolate reductase, which inhibits cell replication by disrupting the normal process of intracellular folate-dependent metabolism, and can simultaneously block three different enzyme targets that are essential for the survival of cancer cells, thereby inhibiting tumor growth.
Pemetrexed disodium is used to treat recurrent locally advanced or metastatic non-small cell lung cancer.
|Product name||Pemetrexed disodium|
|Package details:||1kg/foil bag|
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