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Here's a concise summary of Benzhexol Hydrochloride :
Benzhexol hydrochloride (generic: trihexyphenidyl HCl) is an anticholinergic medication primarily used to:
Treat Parkinson’s disease symptoms (tremor, rigidity, drooling).
Manage drug-induced movement disorders (e.g., side effects of antipsychotics like muscle spasms or restlessness).
Key Points:
Mechanism: Blocks acetylcholine in the brain, rebalancing dopamine.
Common Side Effects: Dry mouth, blurred vision, constipation, dizziness.
Serious Risks:
Worsens glaucoma (avoid if diagnosed).
Confusion/hallucinations (especially in the elderly).
Urinary retention, heat intolerance.
Forms: Tablets (2mg/5mg), oral solution.
Brand: Artane (widely recognized).
Caution: Contraindicated in glaucoma, myasthenia gravis, or bowel obstruction. Use low doses in older adults.
Benzhexol hydrochloride (generic name: Trihexyphenidyl hydrochloride) is a prescription anticholinergic medication primarily used to manage symptoms of Parkinson's disease and drug-induced movement disorders. Here's a concise overview:
Purpose:
Controls tremors, rigidity, and excessive salivation in Parkinson's disease (often combined with levodopa).
Treats drug-induced extrapyramidal symptoms (EPS) caused by antipsychotics (e.g., muscle spasms, restlessness).
Mechanism:
Blocks acetylcholine receptors in the brain, restoring dopamine-acetylcholine balance.
Common Side Effects:
Dry mouth, blurred vision, constipation, urinary retention.
Dizziness, confusion (especially in the elderly).
Serious Risks:
Worsening of glaucoma (contraindicated in angle-closure glaucoma).
Cognitive impairment, hallucinations at high doses.
Heatstroke risk (reduced sweating).
Dosage Forms:
Tablets (2 mg, 5 mg), liquid formulations.
Brand Names: Artane® (most common), others vary by region.
Important Precautions:
Avoid in glaucoma, myasthenia gravis, GI obstruction, or tachycardia.
Use cautiously in elderly patients due to fall/cognitive risks.
Taper gradually to prevent withdrawal symptoms.
Always use under medical supervision—dosing requires individual titration.
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