China Supplier High Quality Best Price D-alpha-Tocopheryl acetate CAS 58-95-7 for Vitamin E for sale
China Supplier High Quality Best Price D-alpha-Tocopheryl acetate CAS 58-95-7 for Vitamin E for sale
China Supplier High Quality Best Price D-alpha-Tocopheryl acetate CAS 58-95-7 for Vitamin E for sale
China Supplier High Quality Best Price D-alpha-Tocopheryl acetate CAS 58-95-7 for Vitamin E for sale
China Supplier High Quality Best Price D-alpha-Tocopheryl acetate CAS 58-95-7 for Vitamin E for sale

China Supplier High Quality Best Price D-alpha-Tocopheryl acetate CAS 58-95-7 for Vitamin E Wholesale & Bulk

D-Alpha-Tocopheryl Acetate is a natural, fat-soluble form of vitamin E (CAS 58-95-7; C₃₁H₅₂O₃) with strong antioxidant properties. A reddish-brown viscous oil, it is insoluble in water but soluble in organic solvents. Used as a nutritional supplement, food preservative, and pharmaceutical ingredient, it prevents oxidative damage in cells, supports cardiovascular health, and enhances skin protection. Commonly found in cosmetics for anti-aging and in animal feed to improve livestock health. More bioactive than synthetic forms (DL-alpha-tocopheryl acetate), it requires light-protected storage. Safe at recommended doses but excessive intake may cause side effects.

Items

Specifications

Results

Appearance

Clear, colourless slightly   greenish-yellow,Viscous,oily liquid,Ph.Eur./USP/FCC

Clear, colourless slightly   greenish-yellow,Viscous,oily liquid

Identification

Positive

Positive

Acidity

USP/FCC

1.0ml,USP/FCC

Residual Solvents

Ph.Eur.2.4.24   USP<467>

To conform(In-house)

Heavy metals

Pb2mg/kg,FCC

Arsenic1mg/kg(in-house)

Copper25mg/kg(in-house)

Zinc25mg/kg(in-house)

Palladium5ppm(in-house)

0.5mg/kg

1mg/kg

2mg/kg

2mg/kg

1ppm

Assay

Ph.Eur.2.2.28(96.5%~102.0%,Ph.Eur.)

99.0%

TAMC

USP<61>Ph.Eur.2.6.12(1000cfu/g,Ph.Eur./USP)

Certified

Conclusion

Conform to Ph.Eur./USP/FCC.

D-Alpha-Tocopheryl Acetate (D-α-Tocopheryl Acetate) is a fat-soluble vitamin E derivative with potent antioxidant properties, widely used in food, pharmaceuticals, cosmetics, and animal feed. Below is a concise overview:

Chemical Information

  • Chemical Name: D-α-Tocopheryl Acetate (Natural Vitamin E)

  • CAS Number: 58-95-7

  • Molecular Formula: C₃₁H₅₂O₃

  • Molecular Weight: 472.74–472.75 g/mol

  • Appearance: Reddish-brown to red viscous oily liquid or semi-solid at room temperature, with a melting point of ~25–28°C and boiling point of 224°C (0.3 mmHg).

Physical & Chemical Properties

  • Solubility: Insoluble in water (<0.1 g/100 mL at 17°C), soluble in ethanol, ether, and organic solvents.

  • Density: 0.953 g/cm³ (25°C).

  • Refractive Index: 1.494–1.498.

  • Stability: Sensitive to light and prone to oxidation; requires storage in dark, cool conditions.

Key Applications

  1. Food Industry

    • Antioxidant: Extends shelf life of oils, margarine, and processed foods by preventing lipid oxidation.

    • Nutritional Supplement: Fortifies foods to combat vitamin E deficiency.

  2. Pharmaceuticals

    • Therapeutic Uses: Treats cardiovascular diseases, fatty liver, hypercholesterolemia, infertility, and menopausal symptoms.

    • Cellular Health: Supports membrane stability and reproductive function.

  3. Cosmetics

    • Anti-Aging: Reduces UV damage, improves skin elasticity, and delays aging.

    • Skin Repair: Enhances barrier function and wound healing.

  4. Animal Feed

    • Health Benefits: Boosts livestock fertility, prevents muscular dystrophy, and supports immune function.

Production Methods

  1. Natural Extraction:

    • Extracts from plant oil deodorizer distillates (e.g., soybean, palm oil).

    • Purified via methanol/glycerol extraction or steam distillation.

  2. Synthesis:

    • Condensation of phytol with trimethylhydroquinone.

    • Acetylation with acetic anhydride under zinc catalysis.

    • Steps:

Safety & Handling

  • Storage: Keep sealed, away from light and oxidizing agents.

  • Handling: Use gloves and goggles to avoid skin contact or inhalation.

  • Toxicity: Non-toxic at recommended doses, but excessive intake may cause diarrhea or metabolic imbalances.

Distinct Features

  • Natural vs. Synthetic: D-α-Tocopheryl Acetate (natural) has 3x higher bioactivity than the synthetic DL-form.

  • Esterified vs. Free: The acetate ester form is more stable and acts as a prodrug, releasing free tocopherol post-ingestion for sustained antioxidant activity.

Summary: D-Alpha-Tocopheryl Acetate is a vital natural antioxidant with superior bioactivity and stability. Its applications in nutrition, healthcare, and cosmetics highlight its irreplaceable role in protecting cells from oxidative damage and supporting overall health.


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