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3,3'-Diamino-4,4'-dihydroxydiphenyl sulfone is used as a pharmaceutical intermediate.
| Items | Technical index |
| Product name | 3,3'-Diamino-4,4'-dihydroxydiphenyl sulfone |
| CAS NO. | 7545-50-8 |
| Molecular formula | C12H12N2O4S |
| Molecular weight | 280.3 |
| Appearance | White powder |
| Purity | 99%min |
| Product parameters | |
| Cas number: | 7545-50-8 |
| Appearance: | White powder |
| Purity: | 99%min |
| Package details: | 1kg/foil bag; 25kg/drum |
| Brand: | Fortunachem |
3,3'-Diamino-4,4'-dihydroxydiphenyl sulfone is a specialized organic chemical compound. Here's a breakdown of what it is and its primary uses.
Structure: It is a diphenyl sulfone derivative, meaning it consists of two benzene rings connected by a sulfone group (-SO2-). Each ring has specific substituents: an amino group (-NH2) and a hydroxyl group (-OH) in adjacent positions (3 and 4, respectively).
Formula: C₁₂H₁₂N₂O₄S
Appearance: Typically a light-colored (tan to brown) crystalline powder.
Key Features: It is a tetrafunctional monomer, meaning it has four reactive sites:
Two primary aromatic amine groups (-NH2)
Two phenolic hydroxyl groups (-OH)
This multifunctionality is what makes it valuable in polymer synthesis.
Its uses are almost exclusively in the field of high-performance polymer synthesis, where it serves as a key building block (monomer or crosslinking agent).
Polybenzoxazines: This is one of its most significant applications. Polybenzoxazines are a relatively new class of thermosetting polymers known for exceptional thermal stability, flame retardancy, low moisture absorption, and good dielectric properties. 3,3'-Diamino-4,4'-dihydroxydiphenyl sulfone is used as a diamine-phenol bifunctional monomer to synthesize benzoxazine resins. These resins, upon curing, form crosslinked polybenzoxazine networks with enhanced glass transition temperatures (Tg) and thermal stability compared to those from simpler monomers. These materials are targeted for aerospace composites, electronic encapsulants, and high-temp adhesives.
Polyimides and Polyamide-imides: It can be used as a diamine monomer in reactions with dianhydrides (e.g., pyromellitic dianhydride) to form sulfone-containing polyimides. The sulfone group introduces polarity, potentially improving adhesion and solubility, while the rigid structure contributes to high-temperature resistance. These are used in films, coatings, and composite matrices.
Epoxy Curing Agent/Hardener: Its two amine groups can react with epoxy resins. The resulting cured network incorporates the rigid diphenyl sulfone structure, leading to epoxies with improved heat resistance, chemical resistance, and mechanical strength at elevated temperatures. This is valuable for advanced composites and structural adhesives.
Polysulfones Modification: While traditional polysulfones like PSU, PES, and PPSU are made from bisphenol S, this monomer can be used to create novel amine- and hydroxyl-functionalized polysulfone oligomers or polymers with different reactivity and property profiles.
The diphenyl sulfone core is present in some pharmaceuticals (e.g., certain antibacterial or antiparasitic drugs like dapsone). While 3,3'-Diamino-4,4'-dihydroxydiphenyl sulfone itself is not a commonly used drug, it serves as a sophisticated chemical intermediate in research laboratories for synthesizing complex molecules for biological testing. Its multiple functional groups allow for selective chemical modifications.
High Thermal & Oxidative Stability: The aromatic rings and sulfone linkage provide rigidity and stability.
Reactivity: The amine and hydroxyl groups allow it to participate in polycondensation (forming polymers with the elimination of water or small molecules) and addition reactions.
Polarity: The sulfone group is highly polar, which can influence the solubility and adhesion properties of the final polymer.
3,3'-Diamino-4,4'-dihydroxydiphenyl sulfone is a specialized, multifunctional monomer primarily used in polymer chemistry to synthesize high-performance thermosetting and thermoplastic materials. Its main value lies in imparting exceptional thermal stability, rigidity, and strength to polymers like polybenzoxazines, polyimides, and advanced epoxies for demanding applications in aerospace, electronics, and advanced composites. Its use as a research chemical for synthesizing bioactive molecules is a secondary, more niche application.




Density: 1.564 g/cm3
Melting point: 231 °C
Boiling point: 596.9ºC at 760 mmHg
Application: Used as a pharmaceutical intermediate

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