Fluoxetine hydrochloride blocks 5-HT2A receptors and restores levels of DA and NE by inhibiting 5-HT2A receptors. At the same time, fluoxetine hydrochloride can also relieve the release of NE and DA by γ-aminobutyric acid (GABA) neurons through the 5-HT2C receptor. In addition to increasing the concentration of 5-HT in the synaptic cleft, it is precisely based on the effect of fluoxetine hydrochloride on 5-HT2A and 5-HT2C that the levels of DA and NE are directly and indirectly restored, with NE and DA de-inhibition properties (NDDI).
Fluoxetine hydrochloride can be used to treat all types of depression, especially for depressive symptoms associated with organic diseases and depression in old age.
|Appearance||White or off-white crystalline powder||Conforms|
|Residue on ignition||≤0.1%||0.04%|
|Cas number:||56296-78-7/ 59333-67-4|
|Appearance:||White or off-white crystalline powder|
|Package details:||1kg/foil bag; 25kg/fiber drum|
A selective serotonin reuptake inhibitor (SSRI), used as an antidepressant.
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