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Fluoxetine hydrochloride blocks 5-HT2A receptors and restores levels of DA and NE by inhibiting 5-HT2A receptors. At the same time, fluoxetine hydrochloride can also relieve the release of NE and DA by γ-aminobutyric acid (GABA) neurons through the 5-HT2C receptor. In addition to increasing the concentration of 5-HT in the synaptic cleft, it is precisely based on the effect of fluoxetine hydrochloride on 5-HT2A and 5-HT2C that the levels of DA and NE are directly and indirectly restored, with NE and DA de-inhibition properties (NDDI).
Fluoxetine hydrochloride can be used to treat all types of depression, especially for depressive symptoms associated with organic diseases and depression in old age.
| Items | Specifications | Results |
| Appearance | White or off-white crystalline powder | Conforms |
| Assay | 98.0~102.0% | 99.95% |
| Residue on ignition | ≤0.1% | 0.04% |
| Water | ≤0.5% | 0.2% |
| pH | 4.5~6.5 | 5.7 |
| Product parameters | |
| Cas number: | 56296-78-7/ 59333-67-4 |
| Appearance: | White or off-white crystalline powder |
| Purity: | 98~102% |
| Package details: | 1kg/foil bag; 25kg/fiber drum |
| Brand: | Fortunachem |
A selective serotonin reuptake inhibitor (SSRI), used as an antidepressant.
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