Pyridostigmine bromide / Mestinon is used to treat myasthenia gravis, functional flatulence after surgery, and urinary retention.
Pyridostigmine bromide can inhibit the activity of cholinesterase and reduce the destruction of acetylcholine released by cholinergic nerve endings, the accumulation of acetylcholine in the synaptic cleft, and the appearance of muscarinic (M) and nicotinic (N) choline receptor excitatory effects. In addition, pyridostigmine bromide has a direct excitatory effect on nicotinic-like choline receptors (N2 receptors) on the exercise endboard and can promote the release of acetylcholine from motor nerve endings, thereby improving muscle tone in the gastrointestinal, bronchial smooth muscle, and systemic skeletal muscle.
|Appearance||White or almost white crystalline powder||Conforms|
|Appearance of solution||Solution is clear and colourless||Conforms|
|Loss on drying||≤0.5%||0.28%|
|Appearance:||White or almost white crystalline powder|
|Package details:||1kg/foil bag; 25kg/drum|
Anticholinergic enzyme for postoperative functional flatulence and urinary retention.
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