Oxaliplatin is used to treat colorectal cancer.
Oxaliplatin crosslinks with DNA through its metabolites inside the cell to form DNA complexes, which in turn terminates the replication of tumor cells, leading to apoptosis. Oxaliplatin induces apoptosis in tumor cells by damaging their DNA, inhibiting DNA and RNA synthesis, and triggering the body's immunological response. Oxaliplatin also has an inhibitory effect on ovarian cancer and melanoma cell lines.
|Appearance||White or almost white crystalline powder||White crystalline powder|
|Specific rotation||+74.5°~ +78.0°||+76.8°|
|Loss on drying||≤0.5%||0.18%|
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|Appearance:||White or almost white crystalline powder|
|Package details:||1g/vial; 100g/foil bag|
It can inhibit the proliferation of colon cancer, ovarian cancer and melanoma cell lines.
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