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![Benzoic acid [2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl] ester CAS 13182-89-3 for sale](/uploads/image/20260114/Benzoylmetronildazole主图.jpg "Benzoic acid [2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl] ester CAS 13182-89-3 wholesale")
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![Benzoic acid [2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl] ester CAS 13182-89-3 for sale](/uploads/image/20250515/Our_Quality_System-Wuhan_Fortuna_20250515.jpg "Benzoic acid [2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl] ester CAS 13182-89-3 wholesale")
Benzoic acid [2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl] ester is an antiparasitic drug.
| Item | Specifications | Results |
| Appearance | White or slightly yellowish crystalline powder or flakes | Slightly yellowish crystalline powder |
| Loss on drying | ≤0.5% | 0.2% |
| Assay | 98.5% - 101.0% | 99.5% |
| Product parameters | |
| Cas number: | 13182-89-3 |
| Appearance: | White or slightly yellowish crystalline powder or flakes |
| Purity: | 98.5% - 101.0% |
| Package details: | 25kg/drum |
| Brand: | Fortunachem |
Benzoylmetronidazole (more accurately, Metronidazole Benzoate) is a benzoate ester prodrug of the antibiotic metronidazole.
It is used as an antiprotozoal and antibacterial agent, particularly for treating infections caused by anaerobic bacteria and certain parasites (e.g., Giardia, Trichomonas). The benzoate form is often used in pediatric oral suspensions because it is less bitter and more palatable than metronidazole itself.
Prodrug Design: It is a classic example of prodrug engineering. The benzoate ester group masks the bitter taste of the parent drug (metronidazole). Once ingested, esterases in the body hydrolyze it, releasing the active metronidazole.
Pharmaceutical Formulation: Its primary chemical use is to solve a formulation problem (palatability) through chemical modification, enabling patient-compliant liquid dosage forms.
Synthetic Chemistry: Its preparation involves a straightforward esterification reaction between metronidazole and benzoyl chloride (or benzoic acid derivatives), a common organic transformation.
Analytical Standard: It serves as a reference standard in quality control labs to verify the identity, purity, and stability of the prodrug in pharmaceutical preparations using techniques like HPLC.
In summary, benzoylmetronidazole is a taste-masked prodrug whose main "chemical use" is as a tool in pharmaceutical chemistry to improve drug properties and patient acceptability through deliberate molecular design.
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