Name: Factory Supply High Quality Cosmetic Grade Polyoxyl 15 hydroxystearate HS15 CAS 70142-34-6 with good service
Brand: Wuhan Fortuna Chemical Co., Ltd.

Detailed Description

Items	Specifications	Results
Appearance(25℃)	Off-white to yellowish paste	Conforms
Identification(TLC)	Must conform	Conforms
Identification(viscosity)	Must conform	Conforms
Identification(free macrogols)	Must conform	Conforms
Identification(IR)	Must conform	Conforms
Appearance of solution	Not more opalescent than reference sol.III,max.B6 or BY6	Conforms
Acid value	Max:1.0 mg KOH/g	0.2
Hydroxyl value	90-110 mg KOH/g	104
Iodine value	Max:2.0 g Iodine/100g	0.4
Peroxide value	Max:3.0 meq/kg	＜1.0
Saponification value	53-63 mg KOH/g	60
Free macrogols	27.0-39.0 g/100g	32.4
Nickel	Max:1 mg/kg	＜1
Water(Karl-Fischer-titration)	Max:0.5 g/100g	0.1
Ph-value(10g/100ml water)	5.0-7.0	6.2
Heavy metals*(test solution:12ml of a 5.0g in 50ml water solution CO₂free)	Must conform(max. 10mg/kg)	Conforms
Freezing point	22-30	Degree C 23
Ethylene oxide	Max:1 mg/kg	＜1
1,4-Dioxane	Max.:10 mg/kg	＜10
Diethylene glycol	Max:620 mg/kg	＜50
Residual solvents acetic acid	Max:0.5 g/100g	0.1
Residual solvents ethylene glycol	Max:620 mg/kg	＜50
Total aerobic microbial count(TAMC) Test method Ph.Eur.,2.6.12	Max:200 CFU/g	＜10
Total combined yeasts/moulds count(TYMC) Test method Ph.Eur.,2.6.12	Max:20 CFU/g	＜10
Escherichia coli Test method Ph.Eur.,2.6.13	Max.:0 CFU/g	0
Staphylococcus aureus Test method Ph.Eur.,2.6.13	Max.:0 CFU/g	0
Pseudomonas aeruginosa Test method Ph.Eur.,2.6.13	Max:0 CFU/g	0
Salmonella Test method Ph.Eur.,2.6.13	Max.:0 CFU/10g	0
Bacterial endotoxins Ph.Eur.,2.6.14 Meth.A	Max.:10 I.U./g	＜3
Elemental impurities	Must conform-ICH Q3D class 1,2A und 3(parenteral conc.limits)	Conforms
Conclusion	The product conforms to the above specifications.

Product Name:Polyoxyl 15 hydroxystearate

CAS:70142-34-6

MF:(C18H36O3.(C2H4O)nH2O)x

Melting point :N/A
form:paste

color:Off-white to yellowish

Uses:

Polyoxyl 15 hydroxystearate (also widely known by its trade names Kolliphor® HS 15 or Solutol® HS 15) is a novel, non-ionic surfactant and emulsifier. Chemically, it is a composite material created by reacting 15 moles of ethylene oxide with 1 mole of 12-hydroxystearic acid. The resulting mixture comprises polyglycerol esters of 12-hydroxystearic acid (about 70%) combined with free polyethylene glycol (about 30%). It is a highly regarded pharmaceutical excipient that meets international pharmacopoeia standards (including USP, Ph.Eur., and the 2025 Chinese Pharmacopoeia).

Key Uses and Selling Points:

If you are evaluating Polyoxyl 15 hydroxystearate for pharmaceutical formulation, drug delivery research, or commercial manufacturing, its primary selling points center around its superior solubilization capabilities, safety profile, and versatility:

Highly Efficient Solubilizer for Poorly Water-Soluble Drugs:
Its most significant advantage is its ability to dramatically enhance the aqueous solubility and dissolution rate of poorly water-soluble (lipophilic) compounds, particularly BCS Class II and IV drugs. It is widely used to formulate challenging APIs for oral and parenteral dosage forms.
Excellent Safety and Tolerability Profile:
Compared to other polyoxyethylene-based surfactants, Polyoxyl 15 hydroxystearate exhibits lower hemolytic activity (less destructive to red blood cells) and low histamine release, which translates to fewer side effects and better patient tolerance.
Advanced Drug Delivery and Bioavailability Enhancement:
Beyond simple solubilization, it can form stable nano-micelles (typically 10-15 nm in size) that act as effective drug carriers. It also enhances the permeability of medium-sized biologics and drugs across epithelial barriers, significantly improving oral bioavailability and intestinal absorption.
Thermal Stability and Sterilization Compatibility:
The compound offers excellent thermal stability, making it highly suitable for formulations that require heat sterilization processes without degrading the excipient.
Versatile Multi-Route Formulation Applications:
It is exceptionally versatile and is successfully utilized across a wide range of dosage forms, including oral capsules, injectables, emulsions, ophthalmic (eye) preparations, nasal drops, and topical formulations (creams, gels, lotions).
Broad Industry Compatibility:
It demonstrates mild compatibility and excellent stability when mixed with various drug components, making it a reliable choice for complex formulations in pharmaceuticals, veterinary medicines, and even cosmetics.

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Also, if you have any other questions, you can contact us
FAQ From Wuhan Fortuna Chemical Co.,Ltd

Q1: Can I get a sample for free ?
A: For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test.
Q2: How to confirm the product quality before placing orders ?
A: Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order.
Q3: What is the payment you accept?
A: For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us.
Q4: What is your shipment way ?
A: For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement.
Q5: How long is your after-sales service?
A: We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company.

Q6: How do you treat quality complaint ?

A: We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers.

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Company Information

Name:Wuhan Fortuna Chemical Co.,Ltd

Category:Others

Trade Category: Trading Company

Employees: 11 - 50 People

Address: Room 2015, No.2 Building, Kaixin Mansion No.107

Company Information: Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.

Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.

We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.

Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.

Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide Polyoxyl 15 hydroxystearate HS15 with good quality and best price, welcome to contact us to get COA/TDS/MSDS of Polyoxyl 15 hydroxystearate HS15.

Our Advantages:

1. Guaranteed purity;

2. Large quantity in stock;

3. Largest manufacturer;

4. Best service after shipment with email;

5. High quality & competitive price;

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