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Ethylenebis(oxyethylenenitrilo)tetraacetic acid is the systematic name for EGTA, a specialized chelating agent. Its key features:
Function: Strongly binds (chelates) metal ions, especially calcium (Ca²⁺).
Selectivity: Highly selective for Ca²⁺ over magnesium (Mg²⁺), binding Ca²⁺ ~100,000 times more tightly. This allows manipulation of Ca²⁺ levels without disrupting Mg²⁺-dependent processes.
Primary Use: Essential in biochemistry and cell biology to buffer or remove free Ca²⁺ ions. It's used to study calcium-dependent signaling, enzyme activity, muscle function, and neuronal processes.
Applications: Found in cell culture media, experimental buffers, and as a contrast agent.
In short: EGTA is a Ca²⁺-specific chelator crucial for research involving calcium signaling.
Item | Specification |
Appearance | White Crystalline Powder |
Assay | 99%min |
Density | 1.2838 (rough estimate) |
Melting point | 241 °C (dec.)(lit.) |
Product parameters | |
Cas number: | 67-42-5 |
Appearance: | White Crystalline Powder |
Purity: | 99%min |
MOQ: | 1kg |
Price: | Negotiable |
Package details: | 1kg/foil bag |
Brand: | Fortuna |
Ethylenebis(oxyethylenenitrilo)tetraacetic acid is the systematic chemical name for EGTA, a specialized chelating agent. Here's a concise breakdown:
Structure:
An ethylene glycol backbone (ethylenebis(oxyethylene
) with nitrogen atoms (nitrilo
) linking to four acetic acid groups (tetraacetic acid
).
Function:
Binds (chelates) metal ions, particularly calcium (Ca²⁺) and magnesium (Mg²⁺).
Key Property:
High selectivity for Ca²⁺ over Mg²⁺ (binds Ca²⁺ ~100,000x more tightly). This makes it invaluable in biological systems where Mg²⁺-dependent processes must continue while Ca²⁺ is sequestered.
Primary Uses:
Buffering/free Ca²⁺ concentrations in biochemical/cell biology experiments.
Studying calcium-dependent processes (e.g., enzyme activation, muscle contraction, neurotransmitter release).
Component of cell culture media and lysis buffers.
Contrast agent in electron microscopy.
In short: EGTA is a Ca²⁺-selective chelator essential for manipulating and studying calcium signaling in biological research. Its complex name precisely describes its chemical structure.
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