Potassium clavulante is a potassium salt having clavulanate as the counterion. It acts as a suicide inhibitor of bacterial beta-lactamase anzymes and has only weak anitbiotic activity when administered alone.
However it can be used in combination with silicon dioxide for treatment of a cariety of bacterial infections, where it prevents antibiotic inactivation by microbial lactaass.
|Appearance||White or almost white powder, hygroscopic||White powder, hygroscopic|
|Related substances||Impurity E: NMT 1.0%||0.033%|
|Impurity G: NMT 1.0%||0.00074%|
|Any other single impurity (major): NMT 0.10%||＜0.05%|
|Total impurities: NMT 2.0%||0.034%|
|Assay (HPLC)||91.2%~107.1% (as content of potassium clavulanate stated on the label)||99.7%|
|CLAV.ACID (as is) 38.3%~45.0%||41.9%|
|CLAV.POT. (as is) 45.6%~53.5%||49.8%|
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