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-2-Amino-1,2-diphenylethanol主图.jpg "Chemical Manufacturer Supply High Quality Best Price (1S,2R)-2-Amino-1,2-diphenylethanol CAS 23364-44-5 with good service wholesale")
(1S,2R)-2-Amino-1,2-diphenylethanol: A Versatile Chiral Reagent
(1S,2R)-2-Amino-1,2-diphenylethanol is a specialized chiral compound valued primarily as a building block in organic synthesis and as a biochemical reagent. Its unique structure makes it an indispensable tool for researchers in chemistry and life sciences.
A key selling point is its role as a precursor for chiral ligands. These ligands are fundamental to asymmetric catalysis, enabling the efficient production of specific molecular enantiomers required in pharmaceutical development. Furthermore, it serves as a critical intermediate in the total synthesis of complex natural products, such as the biologically active alkaloid (-)-angustureine.
In the field of life sciences, this compound demonstrates significant utility as a potent and selective inhibitor of Histone Deacetylase 3 (HDAC3). Its dual reactive sites also provide versatility for various chemical modifications, solidifying its status as a high-value research chemical.
Items | Specifications | Results |
Appearance（25℃） | White or off-white solid | Conforms |
Chemical Purity(HPLC area) | ≥98.0% | 99.8% |
Chiral Purity(HPLC area) | ≥99.0% | 99.9% |
Water(K.F vol) | ≤0.5% | 0.2% |
Conclusion | The product conforms to the above specifications. | |
(1S,2R)-2-Amino-1,2-diphenylethanol is a chiral organic compound primarily used as a valuable building block in chemical synthesis and as a biochemical reagent for life science research.
Based on the provided information, its key selling points are centered on its utility in creating complex molecules and its specific biological activity.
Key Applications and Selling Points
The primary value of (1S,2R)-2-Amino-1,2-diphenylethanol lies in its versatility as a chiral precursor and its function as a selective biological inhibitor.
Chiral Building Block: Its most significant application is as a starting material for synthesizing chiral ligands. These ligands are essential for asymmetric catalysis, a process used to create specific enantiomers of a molecule in various chemical reactions, such as the hydrogenation of dehydroamino acids and the reduction of ketones.
Intermediate in Natural Product Synthesis: It serves as a key intermediate in the multi-step synthesis of complex, biologically active natural products. A prime example is its use in the synthesis of (-)-angustureine, a compound with potential pharmacological activity.
Biochemical Inhibitor: In life science research, (1S,2R)-2-Amino-1,2-diphenylethanol is utilized as a potent and selective inhibitor of Histone Deacetylase 3 (HDAC3), an enzyme involved in gene regulation.
Reactive Versatility: The molecule contains both amine and alcohol functional groups. This allows it to participate in a variety of chemical transformations, such as acylation and condensation reactions, making it a flexible component for creating diverse chemical derivatives.
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