Name: China Factory Supply High Quality Good Price Beta-Arbutin CAS 497-76-7 for skin whitening product
Brand: Wuhan Fortuna Chemical Co., Ltd.

Specifications of Beta-Arbutin CAS 497-76-7

Items	Specifications	Results
Appearance	White crystalline powder	White crystalline powder
Melting point	199~201℃ (±0.5)	199.6~200.3℃
Clarity of water solution	Transparency, colorless, none suspended matters	Conforms
pH value	5.0~7.0	6.1
Specific optical rotation	【α】D²⁰= -66±2º	-66.2º
Arsenic	≤2 ppm	Conforms
Hydroquinone	≤20 ppm	0.28 ppm
Heavy metal	≤20 ppm	Conforms
Loss on drying	≤0.5%	0.05%
Ignition residue	≤0.5%	0.06%
Pathogen	Bacteria：≤300cfu/g	＜20 cfu/g
Pathogen	Fungus：≤100cfu/g	＜20 cfu/g
Assay	≥99.5%	99.65%
Conclusion	The product conforms to the Enterprise Standard.

Parameters of Beta-Arbutin CAS 497-76-7

Product parameters
Cas number:	497-76-7
Appearance:	White crystalline powder
Purity:	99.5%min
Package details:	1kg/foilbag; 25kg/drum
Brand:	Fortunachem

Core Chemical & Industrial Traits

Chemical Nature: A water-soluble, white crystalline powder with a melting point of 195–198°C, stable under neutral to slightly acidic conditions (pH 4–6).
Synthesis Pathways: Commercially produced via two main routes—extraction from plant sources (e.g., Arctostaphylos uva-ursi leaves) or chemical synthesis from hydroquinone and glucose, with synthetic grades offering higher purity (≥98%) and cost-effectiveness.
Key Functional Mechanism: Acts as a selective inhibitor of tyrosinase, a copper-containing enzyme critical for melanin biosynthesis, making it a pivotal active ingredient in cosmetic chemistry.

Industrial & Commercial Applications

Cosmetic & Personal Care Chemicals: The largest application sector, used in whitening serums, creams, lotions, and sunscreens. It is formulated at concentrations of 1–7% (synthetic) or 0.5–3% (natural) to address hyperpigmentation, with compatibility with other skincare actives (e.g., vitamin C, niacinamide).
Food & Beverage Additives: Utilized as a natural antioxidant and flavor enhancer, compliant with food-grade standards (e.g., FCC, USP) to extend shelf life and improve sensory profiles of processed foods.
Pharmaceutical Intermediates: Serves as a precursor in the synthesis of pharmaceutical compounds, leveraging its anti-inflammatory and bacteriostatic properties for topical formulations targeting skin conditions.

Industrial Specifications & Handling

Purity & Quality Control: Industrial-grade Arbutin requires strict quality checks for heavy metal residues (≤10 ppm) and hydroquinone impurities (≤0.1%), adhering to global standards (e.g., ISO, REACH).
Stability & Storage: Packaged in moisture-proof, light-resistant containers (HDPE or aluminum foil bags) to prevent degradation; stable for 24 months under sealed, cool (15–25°C) and dry conditions.
Safety & Regulatory Compliance: Classified as a low-toxicity chemical (LD₅₀ > 5000 mg/kg, oral rat), but industrial handling requires basic PPE (gloves, goggles) to avoid eye/skin irritation from high-concentration dust. It is approved for use in cosmetics by the FDA, EU Cosmetics Regulation (EC 1223/2009), and other regional authorities.