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1,3-Dimethyl-2-imidazolidinone is used as a pharmaceutical intermediate. 1,3-Dimethyl-2-imidazolidinone is used as a high-boiling polar aprotic solvent. It is used as a substitute solvent for toxic hexamethylphosphoramide. It finds application in detergents, dyestuffs, electronic materials and in the manufacture of polymers. It is involved in the preparation of 1,2-bis(trimethylsilyl)benzene. Further, it is utilized as a solvent during alfa-regioselective prenylation of imines. In addition to this, it constitutes the mobile phase during size-exclusion chromatographic analysis of cellulose.
| Items | Specification | Result |
| MW | ≥99.0% | 99.06% |
| Apperance | Colorless and transparent liquid | Colorless and transparent liquid |
| Moisture | ≤0.1% | <0.086% |
| Color | ≤30 | 25 |
| Transmittance | 1.47-1.48 | 1.476 |
| PH | 7-9 | 8.85 |
| Product parameters | |
| Cas number: | 80-73-9 |
| Appearance: | Colorless and transparent liquid |
| Purity: | 99%min |
| Package details: | 200kg/drum |
| Brand: | Fortunachem |
1,3-Dimethyl-2-imidazolidinone, commonly known as DMI, is a cyclic urea derivative with the chemical formula C5H10N2O. It is a colorless, high-boiling, polar aprotic liquid.
Structurally, it is very similar to the well-known solvent NMP (N-Methyl-2-pyrrolidone) but features a five-membered ring containing two nitrogen atoms (an imidazolidinone ring) instead of one. DMI is increasingly used as a "green" replacement for traditional solvents like DMF (Dimethylformamide), NMP, and HMPA in various industrial and laboratory applications.
Here are the key selling points and advantages of DMI:
1. Superior Solvency Power
The Advantage: DMI has an exceptionally high dielectric constant and dipole moment. It is an excellent solvent for a wide range of substances, including polymers (like PVDF, polyimides, and aramids), resins, inorganic salts, and gases.
Why it matters: It can dissolve materials that many other solvents cannot, often allowing for higher solid content in formulations. This makes it ideal for coating applications, battery electrolytes, and polymer processing where complete dissolution is critical for performance.
2. "Green" and Safer Alternative (Regulatory Compliance)
The Advantage: DMI is widely marketed as a safer, more environmentally friendly alternative to NMP and DMF.
NMP has faced strict regulatory restrictions (e.g., REACH in Europe) due to reproductive toxicity concerns.
DMF is classified as a reproductive toxicant and has strict exposure limits.
Why it matters: DMI generally has a more favorable toxicological profile (lower acute toxicity and no current classification as a reproductive toxicant in many jurisdictions, though safety data sheets should always be consulted). Switching to DMI helps manufacturers comply with tightening global environmental regulations without sacrificing performance.
3. High Thermal and Chemical Stability
The Advantage: DMI is stable at high temperatures (boiling point ~224°C) and exhibits strong resistance to hydrolysis, acids, and bases compared to other amide solvents.
Why it matters: It can be used in harsh reaction conditions and high-temperature processes without decomposing. Its low volatility also reduces solvent loss during heating, improving process efficiency and reducing VOC (Volatile Organic Compound) emissions.
4. Low Viscosity and High Selectivity
The Advantage: Despite its high polarity, DMI has relatively low viscosity. It also shows high selectivity in extracting aromatic hydrocarbons from aliphatic ones.
Why it matters: Low viscosity improves handling, pumping, and mixing in industrial processes. Its selectivity makes it valuable in petrochemical refining for purification processes (e.g., extracting benzene or toluene).
5. Enhanced Reaction Rates
The Advantage: As a polar aprotic solvent, DMI effectively solvates cations while leaving anions "naked" and highly reactive.
Why it matters: This significantly accelerates nucleophilic substitution reactions (such as SN2 reactions), often leading to faster reaction times, higher yields, and milder reaction conditions compared to using less polar solvents.
Common Applications
Electronics & Batteries: Used as a solvent or co-solvent in lithium-ion battery electrolytes and for cleaning electronic components due to its high purity and stability.
Polymers & Coatings: Dissolving high-performance polymers for membrane fabrication, wire enamels, and protective coatings.
Agrochemicals & Pharmaceuticals: Serving as a reaction medium for synthesizing active ingredients, replacing restricted solvents like NMP.
Petrochemicals: Used in gas treating and the extraction of aromatics.
Cleaners: Formulating high-performance, low-VOC industrial cleaners and paint strippers.
Summary:
The main selling point of 1,3-Dimethyl-2-imidazolidinone (DMI) is its combination of exceptional solvency power and high thermal stability with a safer, more compliant toxicological profile. It allows industries to replace restricted solvents like NMP and DMF with a high-performance alternative that meets modern environmental and safety standards.




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