Sorafenib tosylate is used in the treatment of advanced liver cancer. Sorafenib tosylate simultaneously inhibits a variety of kinases present in and on the cell surface, including RAF kinase, vascular endothelial growth factor receptor-2 (VEGFR-2), vascular endothelial growth factor receptor-3 (VEGFR-3), platelet-derived growth factor receptor-β (PDGFR-β), KIT, and FLT-3. It can be seen that sorafenib tosylate has a dual anti-tumor effect, on the one hand, it can directly inhibit tumor growth by inhibiting the RAF/MEK/ERK signaling pathway; On the other hand, it can block the formation of tumor neovascularization by inhibiting VEGFR and PDGFR, and indirectly inhibit the growth of tumor cells.
|Product name||Sorafenib tosylate|
|Package details:||1kg/foil bag|
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