Pravastatin sodium treatment of elderly patients with coronary heart disease hyperlipidemia can significantly reduce total cholesterol, low-density lipoprotein, reduce the occurrence of cardiovascular events, no obvious liver and kidney function damage; in addition, pravastatin sodium has a very obvious effect on diabetes mellitus complicated with hyperlipidemia, adverse reactions are relatively rare, suitable for clinical treatment.
Pravastatin sodium can competitively inhibit rate-limiting enzymes in cholesterol anabolism, reducing cholesterol synthesis and concentration in the liver, which will trigger an increase in the expression of low-density lipoprotein (LDL) receptors in the liver, so that more LDL and its precursors in circulation enter the liver, bind to LDL receptors and are eliminated.
|Appearance||White to yellowish white powder or crystalline powder||Conform|
|PH||7.2 – 9.0||8.0|
|Specific rotation||+153°~ +159°||156°|
|Assay||97.0% - 102.0%||99.4%|
|Appearance:||White to yellowish white powder or crystalline powder|
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