The effects of methotrexate are: anti-inflammatory and immunosuppressive. It mainly interferes with the synthesis of intracellular folate, which is the raw material for intracellular DNA and RNA synthesis, so methotrexate can inhibit abnormal proliferation of cells. Especially for those cells that grow quickly, the effect of methotrexate is the most obvious, and for those cells that grow basically stable, the effect is small. Because tumor cells in tumor patients are also abnormally proliferating, the application of methotrexate can kill these cells and achieve the effect of treating tumors.
Methotrexate is used in acute lymphoblastic leukemia, lymphoma, malignant mole, chorionic carcinoma, squamous epithelial carcinoma, lung cancer, cervical cancer, breast cancer and osteogenic sarcoma.
|Appearance||Yellow or orange crystalline powder||Conform|
|Residue on ignition||≤0.1%||0.06%|
|Assay||98.0% - 102.0%||99.7%|
|Appearance:||Yellow or orange crystalline powder|
|Purity:||98.0% - 102.0%|
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