Darifenacin hydrobromide, an orally active, once a day selective M3 receptor antagonist, was launched for the treatment of overactive bladder in patients with symptoms of urge urinary incontinence, urgency and frequency. The drug selectively inhibits M3 receptor in the detrusor muscle while sparing the M1 and M2 receptors that are believed to be involved in central nervous system and cardiovascular function respectively.
Darifenacin hydrobromide is used to treat bladder hyperactivity with symptoms of acute urinary incontinence, urgency, and urinary frequency.
|Appearance||White to off-white powder||White powder|
|Loss on drying||≤1%||0.1%|
|Residue on ignition||≤0.2%||0.05%|
|Appearance:||White to off-white powder|
|Package details:||10g/bottle; 100g/foil bag|
Used as a medication to treat urinary incontinence.
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