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Aliskiren is a potent, highly selective, orally effective, long-acting next-generation antihypertensive drug. Aliskiren is a direct renin inhibitor that blocks renin's conversion of angiotensinogen to angiotensin-type 1 receptors, an early step in the renin-angiotensin system pathway. By inhibiting the subsequent products of renin, angiotensin II, and aldosterone release, aliskiren reduces peripheral vasoconstriction and increases sodium excretion.
|Apperance||Off-white to brown powder||Off-white powder|
|Loss on drying||≤0.5%||0.28%|
|Residue on ignition||≤0.5%||0.16%|
|Appearance:||Off-white to brown powder|
|Package details:||10g,100g,1kg/foil bag;25kg/drum|
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