China Manufacturer Cloxacillin Benzathine CAS 23736-58-5 for sale
China Manufacturer Cloxacillin Benzathine CAS 23736-58-5 for sale
China Manufacturer Cloxacillin Benzathine CAS 23736-58-5 for sale
China Manufacturer Cloxacillin Benzathine CAS 23736-58-5 for sale

China Manufacturer Cloxacillin Benzathine CAS 23736-58-5 Wholesale & Bulk

Cloxacillin benzathine is a broad-spectrum antibiotic that is effective in treating infections caused by Staphylococcus and streptococcus because it absorbs well and rapidly in the intestine, is not disturbed by food, has a high blood concentration, and lasts for a long time.

Cloxacillin benzathine is a long-acting, injectable formulation combining cloxacillin (a penicillinase-resistant β-lactam antibiotic) with benzathine (a diamine salt that slows absorption). Here's a concise overview:

Key Features:

Purpose:

    • Prolongs cloxacillin's release, maintaining therapeutic blood levels for days.

    • Targets penicillinase-producing Staphylococci (e.g., Staphylococcus aureus).

      Uses:

    • Treats/resists bacterial infections (e.g., skin/soft tissue, mastitis in livestock).

    • Often used in veterinary medicine for sustained action.

      Administration:

    • Intramuscular (IM) injection to ensure slow absorption.

      Advantages:

    • Reduces dosing frequency vs. short-acting cloxacillin (e.g., sodium salt).

      Safety:

    • Contraindicated in penicillin-allergic individuals.

    • Potential injection-site reactions (pain, swelling).

Mechanism:

  • Cloxacillin: Inhibits bacterial cell wall synthesis.

  • Benzathine: Delays drug breakdown, extending efficacy.

Note:

While benzathine is common with penicillin G (e.g., Bicillin® for syphilis), cloxacillin benzathine is niche, primarily in veterinary contexts. Always confirm local guidelines for approved uses.

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