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L-Serine: Quick Overview
L-Serine (L-2-amino-3-hydroxypropanoic acid, C₃H₇NO₃) is a conditionally essential amino acid originally isolated from silk. The body synthesizes it from 3-phosphoglycerate, but demand exceeds supply during disease, aging, or stress.
Key Applications
Pharmaceuticals: Core ingredient in compound amino acid infusions; under research for ALS, Alzheimer's, and diabetic neuropathy.
Brain Health: Precursor to phosphatidylserine (PS), a critical brain phospholipid. Enhances memory, focus, and sleep quality.
Cosmetics: A major component of the Natural Moisturizing Factor (NMF), providing hydration and barrier repair.
Food & Feed: Used in sports drinks, nutritional supplements, and animal feed.
Key Selling Points
Brain health & neuroprotection
Natural moisturizing factor for skincare
High safety profile
Cross-industry versatility (pharma, supplements, cosmetics, food, feed)
Strong market growth driven by the Brain Health trend
L-Serine is shifting from a standard nutritional additive to a functional therapeutic ingredient.
Specifications of L-Serine CAS 56-45-1 COA:
Items | Specifications | Results |
Appearance | White crystals or crystalline powder | Conforms |
Assay | 98.5~101.5% | 99.2% |
Residue on ignition | ≤0.1% | 0.04% |
Chloride(Cl) | ≤0.05% | <0.05% |
Sulfate(SO4) | ≤0.03% | <0.03% |
Iron(Fe) | ≤30ppm | <30ppm |
Related Compounds | Not more than 0.5% of any individual impurity is found; Not more than 2.0% of total impurities is found | Conforms |
Specific rotation [α]D25 | +14.0°~+15.6° | +14.6° |
Loss on drying | ≤0.2% | 0.10% |
Conclusion | The product conforms to the Standard Of USP43. | |
CAS:56-45-1
MF:C3H7NO3
Melting point :222 °C (dec.) (lit.)
form:crystalline powder
color:White
Uses:
L-Serine: Comprehensive Overview
What is L-Serine?
L-Serine, chemically known as L-2-amino-3-hydroxypropanoic acid, with the molecular formula C₃H₇NO₃ and a molecular weight of 105.09, is a non-essential amino acid (more precisely, a "conditionally essential amino acid"). It was named after its original isolation from silk protein hydrolysate.
It appears as a white crystalline or crystalline powder, odorless with a sweet taste, readily soluble in water and nearly insoluble in organic solvents such as ethanol and acetone.
Although the healthy human body can synthesize L-serine on its own from the glycolytic intermediate 3-phosphoglycerate, under conditions of disease, aging, oxidative stress, or infection, endogenous synthesis often falls short of physiological demand — which is why exogenous supplementation may be necessary, earning it the designation of a "conditionally essential amino acid."
Core Applications
Pharmaceuticals & Clinical Nutrition
A key raw material in compound amino acid infusions, widely used in third-generation parenteral nutrition formulations and nutritional supplements.
Neuroprotective drug precursor: Research indicates that L-serine can enhance superoxide dismutase (SOD) activity in brain tissue, reduce inflammatory cytokine levels, and improve neurological functional deficits as well as learning and memory impairments.
Under investigation for the treatment of amyotrophic lateral sclerosis (ALS), Alzheimer's disease, and diabetic peripheral neuropathy.
Used in the synthesis of various amino acid derivatives, including cardiovascular drugs, anticancer agents, and protected amino acids for genetic engineering applications.
Brain Health & Cognitive Enhancement (Dietary Supplements)
L-Serine is a core precursor for the synthesis of phosphatidylserine (PS), which constitutes approximately 10%–20% of total brain phospholipids and is a critical component of neuronal cell membranes.
It enhances neuronal membrane fluidity, accelerates neurotransmitter release and receptor binding, and improves memory, focus, and learning capacity.
L-Serine can be converted into D-serine (catalyzed by serine racemase), which serves as an endogenous co-agonist at NMDA receptors and plays a role in learning and memory regulation.
Clinical studies have shown that L-serine supplementation before bedtime can improve sleep quality.
Cosmetics & Skincare
L-Serine is one of the principal components of the Natural Moisturizing Factor (NMF), significantly enhancing skin hydration and barrier repair.
With its unique humectant and moisturizing properties, it is widely incorporated into premium cosmetic formulations (e.g., Avène skin repair moisturizers).
As a constituent of collagen and elastin, it helps maintain skin elasticity and promotes wound healing.
Food & Beverages
Used in sports drinks, amino acid weight-management beverages, and other functional beverages.
Added to various food products as a nutritional supplement.
Animal Feed
Used in animal feed to promote growth and development.
Research & Biotechnology
An important component of cell culture media (especially serum-free formulations).
A biochemical reagent used in peptide synthesis, metabolic pathway research, and microbial fermentation.
Key Selling Points Summary
If you are approaching L-Serine from a commercial sales or product development perspective, here are its core value propositions:
| Selling Point | Details |
|---|---|
| Star Brain Health Ingredient | Precursor to phosphatidylserine (PS); supports memory, focus, and protection against age-related cognitive decline |
| Neuroprotection | Anti-inflammatory, promotes myelin regeneration, improves cerebral blood flow; potential therapeutic applications in ALS and Alzheimer's disease |
| Natural Moisturizing Factor | Cosmetic-grade application with dual benefits of hydration + barrier repair |
| Conditionally Essential Amino Acid | Requires exogenous supplementation during illness or stress — naturally aligns with the supplement market logic |
| High Safety Profile | As a naturally occurring amino acid, it is well-tolerated by the human body with clinical trial support for its safety |
| Multi-Industry Versatility | Spans five major sectors: pharmaceuticals, dietary supplements, cosmetics, food & beverage, and animal feed |
| Strong Market Growth | According to a March 2026 industry report, the global L-Serine market was valued at approximately USD 698 million in 2025 and is projected to reach USD 1.1 billion by 2035, growing at a CAGR of approximately 4.7%–7.3% |
📌 Current Industry Trend: L-Serine is transitioning from a traditional "standard nutritional additive" toward a "functional therapeutic ingredient," with market attention continuing to rise, particularly driven by the Brain Health concept.
Natural food sources rich in L-Serine include: soybeans and soy products, eggs, fish, poultry, nuts, and seeds.






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FAQ From Wuhan Fortuna Chemical Co.,Ltd
Q1: Can I get a sample for free ?
A: For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test.
Q2: How to confirm the product quality before placing orders ?
A: Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order.
Q3: What is the payment you accept?
A: For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us.
Q4: What is your shipment way ?
A: For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement.
Q5: How long is your after-sales service?
A: We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company.
Q6: How do you treat quality complaint ?
A: We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers.



Name:Wuhan Fortuna Chemical Co.,Ltd
Category:Others
Trade Category: Trading Company
Employees: 11 - 50 People
Address: Room 2015, No.2 Building, Kaixin Mansion No.107
Company Information: Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide L-Serine with good quality and best price, welcome to contact us to get COA/TDS/MSDS of L-Serine.
1. Guaranteed purity;
2. Large quantity in stock;
3. Largest manufacturer;
4. Best service after shipment with email;
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