Aprepitant is used to treat vomiting caused by chemotherapy. Aprepitant blocks the action of substance P by binding to NK-1 receptors (mainly present in the central nervous system and its peripherals), and can occupy NK-1 receptors in the brain through the blood-brain barrier, with selectivity and high affinity, while the affinity for NK-2 and NK-3 receptors is low.
|Appearance||White to off-white powder||Off-white powder|
|Any single impurity||≤0.1%||0.06%|
|Appearance:||White to off-white powder|
|Package details:||100g/bottle; 1kg/foil bag|
Aprepitant is a neurokinin-1 (NK-1) receptor antagonist. It is an anticancer chemotherapy vomiting agent.
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