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S-Adenosylmethionine 1,4-butanedisulfonate is an organic intermediate used in the synthesis of SAMe.
| Item | Specifications | Results |
| Appearance | White or off-white, odourless powder | Conform |
| Heavy Metal | ≤10ppm | Conform |
| PH | 1.8～2.5 | 2.20 |
| Residue on ignition | ≤0.1% | 0.08% |
| Sulphate | ≤0.02% | Conform |
| Water | ≤2.8% | 2.74% |
| Assay | ≥ 97.5% | 101.14% |
| Product parameters | |
| Cas number: | 101020-79-5 |
| Appearance: | White or off-white, odourless powder |
| Purity: | 97.5% min |
| Package details: | 1kg/bag |
| Brand: | Fortunachem |
Ademethionine 1,4-Butanedisulfonate is a stable salt form of S-adenosylmethionine (SAMe), a crucial compound naturally produced in the body from methionine and ATP.
Its primary medical use is as a prescription medication for:
Treating Depression: It has demonstrated antidepressant efficacy, particularly for major depressive disorders.
Managing Osteoarthritis: It helps reduce pain and improve joint function, with potential cartilage-protective effects.
Supporting Liver Health: It is used to treat intrahepatic cholestasis (impaired bile flow) in conditions like alcoholic liver disease and cirrhosis, due to its role in detoxification and liver cell membrane repair.
SAMe is the body's primary methyl donor, involved in over 100 biochemical reactions crucial for neurotransmitter synthesis (serotonin, dopamine), joint cartilage maintenance, and liver function. The disulfonate salt form provides enhanced stability for oral administration.
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