English 
Español 
français 
العربية Search
Search
2,5-Dimethoxybenzaldehyde is used as a pharmaceutical intermediate.
2,5-Dimethoxybenzaldehyde (CAS 93-02-7, C₉H₁₀O₃) is a pale-yellow crystalline aromatic aldehyde with methoxy groups at positions 2 and 5. It serves mainly as a pharmaceutical intermediate—notably for the vasopressor methoxamine—and as a versatile building block to acids, alcohols, amines, imines and heterocycles. Minor uses include trace-level fragrance accords, corrosion-inhibitor Schiff bases, analytical reference standards and research chemistry.
Selling points: pre-installed 2,5-substitution saves steps; high purity (≥98% GC); one aldehyde handle enables multiple downstream routes; stable, weighable crystals; scalable supply with CoA/SDS.
Compliance note: it is a monitored precursor to controlled phenethylamines—market strictly as industrial/research use only, require end-use declarations, and never mention drug synthesis.
Items | Specifications | Results |
Appearance | White to Light Yellow Solid | Conforms |
Identity (by IR retention time) | Conforms | Conforms |
Purity(HPLC) | NLT 98.5% | 99.3% |
Water content(K.F.) | NMT 0.5% | 0.19% |
Residue on ignition | NMT 0.5% | 0.31% |
Melting range(℃) | 46-48 | 47 |
Storage | In dry protected from light place in a producer’s package | |
Conclusion | The product conforms to the above specifications. | |
| Product parameters | |
| Cas number: | 93-02-7 |
| Appearance: | Yellowish crystalline powder |
| Purity: | 99%min |
| Package details: | 1kg/foil bag; 25kg/fiber drum |
| Brand: | Fortunachem |
Uses:
2,5-Dimethoxybenzaldehyde (CAS 93-02-7, also called gentisic aldehyde dimethyl ether) is an aromatic aldehyde with the formula C₉H₁₀O₃ (MW 166.17). Its benzene ring carries two methoxy groups at positions 2 and 5 plus an aldehyde group. Physically it appears as pale yellow to beige crystals or crystalline powder, melts at about 46–50 °C, boils around 146 °C/10 mmHg, dissolves readily in methanol, chloroform and ethanol, is only slightly soluble in water, and is somewhat air-sensitive—so it's normally stored sealed, cool and dark.
Chemically it's valued as a building block: the aldehyde group undergoes condensation, oxidation, reduction and reductive amination easily, while the two methoxy groups donate electrons to activate the ring and lock in a specific substitution pattern. That combination of reactive handle + fixed substitution geometry is what makes it useful.
Legitimate Uses
1. Pharmaceutical intermediate (main commercial use)
It is a starting material for methoxamine, an α₁-adrenergic vasopressor used clinically for hypotension; biocatalytic one-pot routes from 2,5-dimethoxybenzaldehyde and pyruvate have been published.
The aldehyde is converted into 2,5-dimethoxybenzoic acid, 2,5-dimethoxybenzyl alcohol, benzylamines, nitrostyrenes and cinnamic acid derivatives — common scaffolds in medicinal chemistry programs targeting CNS, cardiovascular and anti-inflammatory areas.
Used in research labs as a reagent for making Schiff bases, hydrazones and heterocycles during lead discovery.
2. Fragrance & flavor chemistry
As a dimethoxy-substituted benzaldehyde it contributes sweet, powdery, floral-almond nuances and is used at trace levels in accord building and as a precursor to other aroma molecules. Note: it is not a mainstream food additive in the way vanillin or benzaldehyde are; any food use requires checking local flavoring regulations (FEMA/EU status) case by case.
3. Materials & specialty chemicals
Schiff bases derived from it have been studied as corrosion inhibitors for metals (the imine + methoxy donors adsorb onto metal surfaces).
Methoxybenzaldehydes serve as intermediates in some liquid-crystal and optical-material syntheses, and as ligand fragments in coordination chemistry.
4. Analytical & research supply
Sold as a reference standard/reagent (≥97–99% by GC) for chromatography method development, NMR/spectroscopy work and academic organic synthesis teaching labs.
⚠️ Important Compliance Note
Unlike sucrose, this is not a consumer-facing ingredient. 2,5-Dimethoxybenzaldehyde is widely documented as a direct precursor to the 2C family of phenethylamine psychedelics (2C-B, 2C-I, 2C-C etc.), which are controlled substances in most countries. Consequences for your marketing and sales:
Do not mention psychoactive/drug-synthesis applications in any promotional material — doing so creates serious legal exposure and will flag your company with customs and law enforcement.
Expect supplier/customer KYC checks: reputable distributors require end-use declarations, business licenses and may refuse retail sales to individuals.
In many jurisdictions shipments require proper labeling (GHS: skin/eye irritant, respiratory sensitizer H315/H319/H334/H335) and may be monitored by precursor-control programs.
Position the product strictly as "for industrial/pharmaceutical intermediate and research use only — not for human consumption, not for resale to private individuals."
Selling Points (for B2B Copy)
| Angle | How to frame it |
|---|---|
| Fixed 2,5-substitution pattern | Saves customers synthetic steps — the methoxy groups are pre-installed in the exact positions needed, so no extra protection/deprotection or regioselective methylation. |
| High-purity grades available | 98–99% (GC/HPLC), low residual solvent, NMR-conforming structure — critical for pharma intermediate and analytical use. |
| Versatile reactive handle | One aldehyde → acids, alcohols, amines, imines, nitroalkenes, heterocycles; one molecule serves multiple downstream routes. |
| Stable crystalline solid | Easy to weigh, ship and store (mp ~48 °C); non-hygroscopic compared with many liquid aldehydes. |
| Supply-chain reliability | Mature Vilsmeier/formylation route from 1,4-dimethoxybenzene; scalable to ton-level with consistent batch-to-batch quality; CoA + SDS provided. |
| Niche, high-value positioning | Small-volume, high-margin fine chemical — ideal for custom synthesis/CRO clients rather than price-war commodity markets. |
Suggested tagline direction: "A precise 2,5-dimethoxy scaffold, one aldehyde handle — your shortcut to complex aromatic intermediates."
Also, if you have any other questions, you can contact us
FAQ From Wuhan Fortuna Chemical Co.,Ltd
Q1: Can I get a sample for free ?
A: For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test.
Q2: How to confirm the product quality before placing orders ?
A: Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order.
Q3: What is the payment you accept?
A: For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us.
Q4: What is your shipment way ?
A: For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement.
Q5: How long is your after-sales service?
A: We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company.
Q6: How do you treat quality complaint ?
A: We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers.
Name:Wuhan Fortuna Chemical Co.,Ltd
Category:Others
Trade Category: Trading Company
Employees: 11 - 50 People
Address: Room 2015, No.2 Building, Kaixin Mansion No.107
Company Information: Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide 2,5-Dimethoxybenzaldehyde with good quality and best price, welcome to contact us to get COA/TDS/MSDS of 2,5-Dimethoxybenzaldehyde.
1. Guaranteed purity;
2. Large quantity in stock;
3. Largest manufacturer;
4. Best service after shipment with email;
5. High quality & competitive price;
Used as pharmaceutical intermediate.
Fortunachem Provides Not Only Professional Chemical Products But Also Professional Help
Keeping you up-to-date with all the latest information, news, and events about Fortunachem!
Quick Links
Add:
E-mail:
中文
