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Gemcitabine is used for advanced and metastatic pancreatic cancers and is also indicated for the treatment of intermediate and advanced non-small cell lung cancers.
Gemcitabine mainly acts on the DNA synthesis phase, that is, the S phase, and under certain conditions, it can prevent the progression of the G1 phase to the S phase. Gemcitabine has the characteristics of broad anticancer spectrum, unique mechanism of action, low toxicity, no cross-resistance to other chemotherapy drugs, and no superposition of toxic reactions.
| Items | Specification | Result |
| Assay | 98.0%-102.0% | 99.1% |
| Apperance | White crystalline powder | Complies |
| Heavy metals | ≤010ppm | Complies |
| Residue on ignition | ≤0.2% | 0.03% |
| Related substances | Impurity A≤0.1% Impurity B≤0.1% Total impurities≤1.0% | 0.03% 0.03% 0.05% |
| Loss on drying | ≤5.0% | 0.1% |
| Product parameters | |
| Cas number: | 95058-81-4 |
| Appearance: | White crystalline powder |
| Purity: | 98%-102% |
| Package details: | 100g,1kg/foil bag;25kg/drum |
| Brand: | Fortunachem |
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