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Diethyl ethoxymethylenemalonate is used as an intermediate for chloroquine, norfloxacin and lomefloxacin.
Diethyl ethoxymethylenemalonate is used for synthesis of pyrido[3,2-e]pyrimido[1,2-c]pyrimidines. Initially, it was used to monitor lysine decarboxylase activity. It is useful in the determination of amino acids by precolumn derivatization by using reversed-phase high-performance liquid chromatography (HPLC). It plays an important role in the Gould-Jacobs reaction to prepare quinolines. For example, anile reacts with this reagent to give 4-hydroxyquinoline. It acts as an intermediate in the production of flumequine, which is a fluoroquinolone antibiotic.
| Product Name | Diethyl ethoxymethylenemalonate |
| Apperance | Colorless liquid |
| EINECS | 201-725-7 |
| MF | C10H16O5 |
| MW | 216.23 |
| Assay | ≥99.0% |
| Product parameters | |
| Cas number: | 87-13-8 |
| Appearance: | Colorless liquid |
| Purity: | 99%min |
| Package details: | 200kg/drum |
| Brand: | Fortunachem |

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