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Adenine is an organic base, adenine and guanine together constitute the two main purine bases in nucleic acids, which combine with ribose or deoxyribose through glycosidic bonds to form adenosine or deoxyadenosine; The compounds of triphosphate are adenosine diphosphate and deoxyadenosine triphosphate, which are precursors of adenine in the process of ribonucleic acid and deoxyribonucleic acid biosynthesis. In addition, adenine is contained in cyclic AMP and many coenzymes, so it plays an important role in cellular metabolism and energy exchange.
Adenine CAS 73-24-5 is a component of nucleic acids that are involved in RNA and DNA synthesis in living organisms. When leukocytes are deficient, an adenine can promote the increase of leukocytes, which is used to prevent leukopenia and is also used for acute granulocytopenia.
Adenine is used to prevent and treat leukopenia and acute neutropenia caused by various causes, especially leukopenia caused by tumor chemotherapy, radiotherapy and benzene poisoning.
| Items | Specification | Results |
| Appearance | White crystalline powder | Complies |
| Loss on drying | ≤1.0% | 0.1% |
| Residue on ignition | ≤0.1% | 0.1% |
| Assay(HPLC) | 98.0%～102.0% | 100.4% |
| Product parameters | |
| Cas number: | 73-24-5 |
| Appearance: | White crystalline powder |
| Purity: | 98~102% |
| Package details: | 25kg/drum |
| Brand: | Fortunachem |
Adenine, a purine nucleobase, has several important applications across various fields, including biochemistry, medicine, and biotechnology. Here are some key applications:
### 1. **DNA and RNA Synthesis**
- Adenine is one of the four nucleobases in **DNA** (along with thymine, cytosine, and guanine) and **RNA** (where thymine is replaced by uracil). It plays a crucial role in genetic coding and protein synthesis.
### 2. **ATP (Adenosine Triphosphate)**
- Adenine is a component of **ATP**, the primary energy carrier in cells. ATP is essential for metabolic processes, muscle contraction, and cellular signaling.
### 3. **NAD and FAD (Coenzymes)**
- Adenine is part of **NAD (Nicotinamide Adenine Dinucleotide)** and **FAD (Flavin Adenine Dinucleotide)**, which are critical for redox reactions in cellular respiration and energy production.
### 4. **Pharmaceuticals & Medicine**
- **Antiviral & Anticancer Drugs**: Adenine derivatives (e.g., **acyclovir**, **fludarabine**) are used in antiviral and chemotherapy treatments.
- **Immunosuppressants**: Drugs like **azathioprine** (used in organ transplants) contain adenine derivatives.
- **Vitamin B4**: Adenine was historically referred to as Vitamin B4, though it is no longer classified as a vitamin since it is synthesized by the body.
### 5. **Biotechnology & Molecular Biology**
- Used in **PCR (Polymerase Chain Reaction)** and DNA sequencing.
- Adenine-rich sequences are used in **gene probes** and **primer design**.
### 6. **Nutritional Supplements**
- Sometimes included in cell culture media to support nucleic acid synthesis in lab-grown cells.
### 7. **Chemical Research**
- Adenine derivatives are studied for potential applications in **organic electronics** and **nanotechnology** due to their hydrogen-bonding properties.
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