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As a third-generation quinolone synthetic antibacterial drug, ofloxacin has the advantages of wide antibacterial spectrum, strong antibacterial activity, good bioavailability, safe and effective oral administration, low toxicity and no drug resistance. It has a good antibacterial effect on a variety of gram-positive and gram-negative bacteria, and also has antibacterial effect on Pseudomonas aeruginosa and chlamydia. Strains resistant to neopenicillin, clincomycin, gentamicin, and strains resistant to haloperic acid have good effects and no cross-resistance. In addition, it also has a certain antibacterial effect on anaerobic bacteria.
Ofloxacin is mainly used for acute and chronic infections of the respiratory tract, throat, tonsils, urinary tract, prostate, skin and soft tissues, intestines and otolaryngology caused by sensitive bacteria.
Items | Specifications | Results |
Appearance | White to light yellowish crystalline powder | Conforms |
Identification | IR、UV, Meet the requirements | Conforms |
Specific rotation | -1 ~ +1° (25℃) | 0° |
Related substances | Individual impurity≤0.3% | 0.07% |
Total impurities≤0.5% | 0.16% | |
Loss on drying | ≤0.2% | 0.15% |
Residue on ignition | ≤0.1% | 0.05% |
Arsenic | ≤1ppm | <lppm |
Residual solvents | Methanol≤0.005% | N.D. |
Ethanol≤0.05% | N.D. | |
Assay | 98.5~101.5% (on dry basis) | 99.3% |
Conclusion | The product conforms to the Enterprise Standard. | |
| Product parameters | |
| Cas number: | 82419-36-1 |
| Appearance: | A white or light yellow crystalline power |
| Purity: | 98.5%min |
| Package details: | 25kg/drum |
| Brand: | Fortunachem |
Ofloxacin is a synthetic antibiotic belonging to the fluoroquinolone class. It works by inhibiting two bacterial enzymes (DNA gyrase and topoisomerase IV), which prevents bacteria from replicating and repairing their DNA.
It is a broad-spectrum antibiotic, meaning it is effective against a wide range of bacteria. It is commonly used to treat various infections, including:
Respiratory tract infections (e.g., pneumonia, bronchitis)
Urinary tract infections (UTIs)
Skin infections
Prostatitis
Certain sexually transmitted infections (STIs) like gonorrhea
Important Considerations:
It is available in oral (tablet) and topical (ear/eye drops) forms.
Side effects can include nausea, diarrhea, insomnia, and, more seriously, tendonitis or nerve damage.
Due to these risks, it is typically reserved for infections not treatable by safer antibiotics.
It should be used only under the supervision of a doctor.
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