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L-Carnitine is used in medicine, nutraceuticals, functional drinks, feed additives, etc.
L-Carnitine is a naturally occurring quaternary ammonium compound that serves as the obligatory molecular shuttle for transporting long-chain fatty acids across the inner mitochondrial membrane, where they undergo β-oxidation to generate ATP. Without adequate L-Carnitine, fatty acids cannot enter the mitochondria for oxidation — regardless of caloric deficit or exercise intensity.
In sports nutrition, L-Carnitine enhances fat oxidation rates by 10–25% during aerobic exercise, spares muscle glycogen to extend endurance, reduces blood lactate accumulation, and accelerates recovery by attenuating muscle damage markers. Its non-stimulant, exercise-synergistic profile differentiates it from caffeine or thermogenic agents — it optimizes the body's intrinsic fat-burning machinery at the mitochondrial level rather than suppressing appetite or increasing metabolic rate.
L-Carnitine is a foundational ingredient in pre-workout fat-burning complexes, stimulant-free weight management formulas, and keto-adaptation supplements — making it a go-to choice among fitness-focused consumers for targeted fat loss and body shaping.
Items | Specifications | Results |
Appearance(25℃) | White crystals or crystalline powder | White crystalline powder |
Identification | Infrared or chemical methods | Positive reaction |
Appearance of the solution | Clear and colorless | Conforms |
Specific Rotation | -29.0°~-32.0° | -31.36° |
Residue On Ignition | ≤0.1% | 0.04% |
Loss on drying | ≤0.5% | 0.24% |
PH | 5.5~9.5 | 6.64 |
Assay | 97.0%~103.0% | 99.40% |
D-Carnitine | ≤0.2% | 0.06% |
Residue Ethanol | ≤0.5% | ＜0.5% |
Heavy Metals | ≤10ppm | ＜10ppm |
Arsenic (As) | ≤1ppm | ＜1ppm |
Chloride | ≤0.4% | ＜0.4% |
Potassium | ＜0.2% | |
Sodium | ≤0.1% | ＜0.1% |
Cyanide | Negative | Negative |
Lead | ≤3ppm | ＜3ppm |
Mercury | ≤0.1ppm | ＜0.1ppm |
Cadmium | ≤1ppm | ＜1ppm |
Total Plate Count | ≤1000cfu/g | 30cfu/g |
Yeast & Mold | ≤100cfu/g | 20cfu/g |
E.Coli | Negative | Negative |
Salmonella | Negative | |
Storage | Store in cool & dry place . Do not freeze. | |
Conclusion | The product conforms to the above specifications. | |
| Product parameters | |
| Cas number: | 541-15-1 |
| Appearance: | White crystals or white crystalline power |
| Purity: | 97.0 ～103.0% |
| Package details: | 25kg/drum |
| Brand: | Fortunachem |
Uses:
L-Carnitine — Mitochondrial Fat Transporter for Body Shaping & Fat Loss
CAS No: 541-15-1
L-Carnitine (β-hydroxy-γ-trimethylammonio butyrate) is a naturally occurring quaternary ammonium compound synthesized endogenously in the liver and kidneys from the amino acids L-lysine and L-methionine, with additional dietary intake from red meat and dairy products. As a conditionally essential nutrient, L-Carnitine plays an irreplaceable role in lipid metabolism — it is the obligatory molecular shuttle responsible for transporting long-chain fatty acids (LCFAs) across the inner mitochondrial membrane into the mitochondrial matrix, where they undergo β-oxidation to generate adenosine triphosphate (ATP), the primary energy currency of cells. Without adequate L-Carnitine availability, long-chain fatty acids cannot enter the mitochondria for oxidation, regardless of caloric deficit or exercise intensity.
Core Mechanism: Mitochondrial Fatty Acid Transport
The carnitine shuttle system operates through a precisely coordinated three-enzyme process:
Carnitine Palmitoyltransferase I (CPT I), located on the outer mitochondrial membrane, conjugates activated long-chain acyl-CoA with free carnitine to form acylcarnitine esters.
Carnitine-Acylcarnitine Translocase (CACT) shuttles acylcarnitine across the inner mitochondrial membrane in exchange for free carnitine.
Carnitine Palmitoyltransferase II (CPT II), on the inner mitochondrial membrane, regenerates acyl-CoA inside the matrix for β-oxidation.
This transport mechanism is the rate-limiting step in fat oxidation — making L-Carnitine availability a direct determinant of how efficiently the body can mobilize and burn stored fat for energy, particularly during exercise when fatty acid demand is elevated.
Functional Benefits in Sports Nutrition, Fitness & Slimming
Enhanced Fat Oxidation During Exercise: During moderate-intensity endurance exercise (60–70% VO₂max), fatty acids serve as the primary fuel source. L-Carnitine supplementation has been shown to increase the rate of fat oxidation by 10–25% during sustained aerobic activity, effectively shifting the body's fuel utilization toward greater lipid oxidation and reduced carbohydrate dependence. This "fat-burning efficiency" is particularly valuable for athletes pursuing body recomposition — losing fat while preserving lean muscle mass.
Glycogen Sparing & Endurance Extension: By increasing the proportion of energy derived from fat oxidation, L-Carnitine reduces the rate of muscle glycogen depletion during prolonged exercise. This glycogen-sparing effect delays the onset of fatigue, extends time-to-exhaustion, and supports higher training volumes — enabling more frequent and intense workouts that drive greater caloric expenditure and body shaping results.
Lactate Buffering & Recovery Acceleration: L-Carnitine supplementation has been associated with reduced blood lactate accumulation during high-intensity exercise and faster post-exercise lactate clearance. By promoting fatty acid oxidation as an alternative energy pathway, it reduces the glycolytic burden on working muscles. Additionally, L-Carnitine attenuates exercise-induced muscle damage by reducing markers such as creatine kinase (CK) and malondialdehyde (MDA), accelerating recovery between training sessions.
Metabolic Flexibility & Insulin Sensitivity: L-Carnitine improves the muscle's capacity to switch between carbohydrate and fat oxidation substrates — a concept known as metabolic flexibility. Enhanced metabolic flexibility is strongly correlated with improved insulin sensitivity, reduced visceral adiposity, and lower risk of metabolic syndrome. For fitness enthusiasts, this translates to more efficient nutrient partitioning — directing calories toward muscle glycogen replenishment rather than fat storage.
Reduction of Exercise-Induced Muscle Soreness (DOMS): Clinical studies have demonstrated that L-Carnitine supplementation (2–3 g/day for 2–3 weeks prior to exercise) significantly reduces delayed-onset muscle soreness and preserves muscle function after eccentric exercise, enabling more consistent training adherence — a critical factor for long-term body shaping success.
Classification: Energy Metabolite with Primary Fat-Loss Application
While L-Carnitine is classified within the energy metabolism category of sports nutrition ingredients — alongside compounds such as CoQ₁₀, creatine, and B-vitamins — its core functional differentiation lies in its direct role as a fat transporter rather than a direct energy substrate. Unlike caffeine (which mobilizes fatty acids from adipose tissue via catecholamine release) or medium-chain triglycerides (which bypass the carnitine shuttle entirely), L-Carnitine operates at the mitochondrial membrane level, governing the actual entry of fatty acids into the oxidation pathway. This makes it a uniquely targeted ingredient for fat loss — not by suppressing appetite or stimulating thermogenesis, but by optimizing the body's intrinsic fat-burning machinery.
Differentiation from Other Fat-Loss Ingredients
| Feature | L-Carnitine | Caffeine | Green Tea Extract (EGCG) | CLA |
|---|---|---|---|---|
| Primary Mechanism | Mitochondrial FA transport | CNS stimulation / lipolysis | Thermogenesis / lipolysis | Adipocyte modulation |
| Caloric Expenditure Effect | Indirect (↑ fat oxidation) | Direct (↑ BMR) | Direct (↑ thermogenesis) | Minimal |
| Stimulant Properties | Non-stimulant | Stimulant | Mild stimulant | Non-stimulant |
| Exercise Dependency | Efficacy enhanced by exercise | Works at rest & exercise | Works at rest & exercise | Independent of exercise |
L-Carnitine's non-stimulant, exercise-synergistic profile makes it uniquely suited for stacking with other fat-loss ingredients and for use by individuals sensitive to stimulants or those following evening training protocols where caffeine intake is contraindicated.
Preferred Applications
Pre-workout fat-burning complexes (stacked with caffeine, green tea extract, or yohimbine)
Intra-workout endurance beverages (glycogen-sparing formulation)
Post-workout recovery formulas (DOMS reduction and muscle preservation)
Daily fat-loss capsules and softgels (2–3 g L-Carnitine tartrate or acetyl-L-carnitine)
Clean-label, stimulant-free weight management products
Keto-adaptation support supplements (enhancing fat oxidation during ketogenic dietary transitions)
L-Carnitine has established itself as a foundational ingredient in fat-loss and body shaping formulations, valued by fitness-oriented consumers for its scientifically validated role in mitochondrial fat transport, its non-stimulant safety profile, and its synergistic compatibility with exercise — making it not merely a supplement, but a metabolic optimizer that enhances the body's innate capacity to burn fat for fuel.
Also, if you have any other questions, you can contact us
FAQ From Wuhan Fortuna Chemical Co.,Ltd
Q1: Can I get a sample for free ?
A: For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test.
Q2: How to confirm the product quality before placing orders ?
A: Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order.
Q3: What is the payment you accept?
A: For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us.
Q4: What is your shipment way ?
A: For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement.
Q5: How long is your after-sales service?
A: We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company.
Q6: How do you treat quality complaint ?
A: We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers.
Name:Wuhan Fortuna Chemical Co.,Ltd
Category:Others
Trade Category: Trading Company
Employees: 11 - 50 People
Address: Room 2015, No.2 Building, Kaixin Mansion No.107
Company Information: Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical and Intermediates, Food and Feed additives, Fine chemicals,Biochemical and Reagent, which is the members of Hubei E-commerce Chamber.
Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement.
We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves.
Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward power, their satisfaction is our struggling goal.
Wuhan Fortuna Chemical Co.,Ltd is a professional manufacturer which provide L-carnitine with good quality and best price, welcome to contact us to get COA/TDS/MSDS of L-carnitine.
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