Chloramphenicol has inhibitory effects on gram-negative bacteria, gram-positive bacteria, etc. It can be used to treat typhoid diarrhea, urinary tract infections, whooping cough, pneumonia, sepsis and other diseases.
Chloramphenicol acts by inhibiting bacterial protein synthesis. It binds to the 50S subunit reversibility on the bacterial 70S ribosome, thereby preventing the aminoacyl tRNA's amino acid terminus from binding to receptors on the ribosome. In this way, the amino acid substrate cannot interact with transpeptidases and thus cannot form peptide bonds. Chloramphenicol is usually a bacteriostatic agent, but it can also kill common meningeal pathogens such as influenza bacilli, meningococcus, and pneumococcus at therapeutic concentrations.
|Appearance||White, greyish-white or yellowish-white crystalline powder||Yellowish-white crystalline powder|
|Loss on drying||≤0.3%||0.1%|
|Residue on ignition||≤0.1%||0.04%|
|Appearance:||White, greyish-white or yellowish-white crystalline powder|
|Package details:||1kg/foil bag;25kg/drum|
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