Celecoxib CAS 169590-42-5 for sale
Celecoxib CAS 169590-42-5 for sale
Celecoxib CAS 169590-42-5 for sale

Celecoxib CAS 169590-42-5 Wholesale & Bulk

Celecoxib has the anti-inflammatory and analgesic effect of NSAIDs. Because of its chemical structure, it can be combined with COX-2, selectively inhibiting COX-2. Its phenyl group binds with the hydrophobic channel of COX-2, and its hydrophilic sulfonamide forms a hydrogen chain with 513 arginine and 90 histidine in the COX-2 "side pocket. It is also in close contact with arginine in the COX-2120 position and plays a role in inhibiting COX-2 from converting arachidonic acid to prostaglandins which are harmful to the human body. Due to subtle differences between the structures of COX-1 and COX-2, Celecoxib cannot enter the COX-1 molecule, nor inhibit its transformation of arachidonic acid into prostaglandins.  Thus, it has good anti-inflammatory and analgesic effects, protects gastric mucosa, protects renal blood flow, regulates platelet aggregation, and resolves the gastric irritation problems of commonly used NSAIDs.

Celecoxib is a new generation of nonsteroidal anti-inflammatory analgesics that inhibit prostaglandin production by selectively inhibiting cyclooxygenase-2 (COX-2) to achieve anti-inflammatory and analgesic effects.

Specifications of Celecoxib CAS 169590-42-5

CharactersThe white or almost white crystalline powderThe almost white crystalline powder
Heavy metals≤0.002%<0.002%
Loss on drying≤0.5%0.02%
Sulfated ash≤0.1%0.04%
Related substanceSingle impurity≤0.5%0.21%
Total impurities≤1.0%0.23%

Parameters of Celecoxib CAS 169590-42-5

Product parameters
Cas number:169590-42-5
Appearance:Almost white crystalline powder
Purity:99.0% min
Package details:1kg/foil bag, 25kg/drum

Packing of Celecoxib CAS 169590-42-5 Wholesale

Packing of Celecoxib CAS 169590-42-5

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