Name: Manufacturer Supplier Top Purity Bulk Price trans Latanoprost CAS 913258-34-1 with good service
Brand: Wuhan Fortuna Chemical Co., Ltd.

Items	Specifications	Results
Appearance	Colorless to yellowish viscous oil liquid	Conforms
Identification	HPLC: Sample and standard exhibits same retention time	Conforms
Water	≤0.5%	0.20%
Loss on drying	≤1.0%	0.31%
Residual on solvents	Ethanol:≤0.5%	0.30%
Total impurities	≤5.0%	3.90%
Purity	≥95.0%	96.1%
Conclusion	The product conforms to the Enterprise Standard.

trans-Latanoprost (also known as Latanoprost Impurity A or (5E,15S)-Latanoprost, CAS No. 1235141-39-5) is a specific geometric isomer and impurity of the active pharmaceutical ingredient (API) Latanoprost.

Chemical Nature: While commercial Latanoprost contains a cis double bond at the 5,6-position of the heptenoate chain, trans-Latanoprost features a trans (E) configuration at this position. It also typically refers to the 15S stereoisomer.

Primary Use: It is not a therapeutic drug itself. Instead, it serves as a critical reference standard and impurity marker in the pharmaceutical industry.

Quality Control (QC): Used to validate HPLC/GC methods to ensure the final Latanoprost drug product (used for glaucoma treatment) meets strict purity limits (usually <0.1% or <0.5% for this impurity).

Stability Studies: Used to monitor the degradation of Latanoprost formulations over time, as the cis-to-trans isomerization can occur under stress conditions (light, heat).

Process Development: Helps chemists optimize synthesis routes to minimize the formation of this unwanted isomer.

Key Selling Points

Targeted at pharmaceutical manufacturers, QC laboratories, and regulatory affairs departments, the selling points include:

High Purity & Characterization:

Supplied with high chemical purity (>95% or >98%) and confirmed stereochemistry. Essential for accurate calibration and reliable impurity quantification.

Comprehensive characterization data provided (NMR, MS, IR, HPLC) to support regulatory filings (IND/NDA/ANDA).

Regulatory Compliance:

Manufactured and documented in accordance with ISO 17034 (Reference Material Producer) guidelines.

Includes a detailed Certificate of Analysis (COA) traceable to international standards, crucial for FDA, EMA, and NMPA audits.

Critical for Safety & Efficacy Validation:

Enables manufacturers to prove their product is free from excessive levels of this specific geometric isomer, ensuring patient safety and drug efficacy.

Stability & Packaging:

Packaged in light-resistant, temperature-controlled vials to prevent isomerization during storage, guaranteeing the integrity of the reference standard.

Global Supply for Generic Drug Approval:

Essential for generic drug companies seeking approval; having access to certified impurity standards is a mandatory requirement for demonstrating bioequivalence and quality parity with the brand-name drug (Xalatan).

Important Notice: This product is sold strictly as a chemical reference standard or research material for laboratory quality control and analytical purposes only. It is not for human or animal administration, nor for use as a finished pharmaceutical product.