Name: Manufacturer Supplier High Quality Bulk Price 1,3,5-Tri-O-benzoyl-2-O-methyl-D-ribose CAS 68045-07-8
Brand: Wuhan Fortuna Chemical Co., Ltd.

1,3,5-Tri-O-benzoyl-2-O-methyl-D-ribose (CAS No. typically 68045-07-8, though isomers exist) is a chemically modified ribose derivative, specifically a protected sugar intermediate used in carbohydrate chemistry.

Chemical Structure: It is a derivative of D-Ribose where:

The hydroxyl group (-OH) at the 2-position is methylated (-OCH₃), which locks its chemical properties or influences stereochemistry.
The hydroxyl groups at the 1, 3, and 5-positions are protected with benzoyl groups (-COC₆H₅). Benzoyl groups are common protecting groups that prevent unwanted side reactions at these positions during subsequent synthetic steps and can be removed under specific conditions.

Primary Applications: It serves as a crucial organic synthesis intermediate, primarily in the pharmaceutical and biotechnology sectors for synthesizing:

Nucleoside Analogs: As a building block for creating bioactive nucleoside derivatives (e.g., antiviral drugs, anticancer agents).
Oligonucleotides: For research into RNA/DNA analogs.
Chiral Synthesis: Due to its specific stereochemical configuration, it is valuable in asymmetric synthesis for introducing chiral centers.

Key Selling Points

Targeted at professional buyers (pharmaceutical companies, CROs, research laboratories), the core selling points for this product include:

High Regioselectivity and Stereochemical Purity:

Offers high-purity specific alpha or beta isomers (e.g., >98% or >99% by HPLC), ensuring stereospecificity in downstream synthesis, minimizing byproducts, and improving the yield of final drug candidates.

Essential Synthetic Building Block:

An indispensable "brick" for synthesizing various blockbuster drugs (such as certain antiviral nucleoside medications). Given the complexity of its synthesis, purchasing high-quality ready-made material is often more cost-effective and time-efficient than in-house production.

Robust Protecting Group Strategy:

The benzoyl protecting groups offer excellent stability under various reaction conditions, while the 2-O-methylation provides a unique window of reactivity, allowing chemists to perform targeted modifications at specific sites.

Regulatory Compliance and Traceability:

Supplied with comprehensive documentation, including Certificates of Analysis (COA), Material Safety Data Sheets (MSDS/SDS), and detailed impurity profiles, meeting GMP or stringent research-grade standards to satisfy pharmaceutical industry audit requirements.

Scalable Supply Capability:

Capable of supporting scale-up from gram-level R&D to kilogram or even ton-level commercial production, ensuring a reliable supply chain for clients' evolving needs.

Important Notice: As stated in previous disclaimers, this product is sold strictly as an industrial raw material for legal research and manufacturing purposes only. Direct application to humans or animals is prohibited. Violators bear full liability.