Name: Chemical Factory High Quality Best Price N-Boc-L-alaninol CAS 79069-13-9 with good service
Brand: Wuhan Fortuna Chemical Co., Ltd.

Items	Specifications	Results
Appearance(25℃)	White or off-white powder	Pass test
Purity	≥98%	99.2%
Any single impurity	≤0.5%	0.15%
Conclusion	The product conforms to the above specifications.

N-Boc-L-alaninol (also known as N-Boc-L-丙氨醇 or (S)-2-(tert-Butoxycarbonylamino)-1-propanol) is a chiral chemical intermediate widely used in organic synthesis, particularly in the pharmaceutical and agrochemical industries.

Here is a detailed breakdown of what it is and its key selling points:

1. What is N-Boc-L-alaninol?

Chemical Structure: It is the N-protected derivative of L-alaninol (the alcohol reduced form of the amino acid L-alanine). The "Boc" stands for tert-butyloxycarbonyl, a common protecting group for amines.

Formula: C₈H₁₇NO₃

Molecular Weight: 175.23 g/mol

CAS Number: 79069-13-9

Appearance: Typically a white to off-white solid (melting point ~59–62 °C).

Chirality: It possesses a specific stereochemistry ((S)-configuration), derived from natural L-alanine, which is crucial for synthesizing biologically active molecules.

2. Key Selling Points & Applications

The "selling points" of N-Boc-L-alaninol revolve around its utility as a high-value building block in asymmetric synthesis:

A. Chiral Building Block for Drug Synthesis

Enantiomeric Purity: It provides a reliable source of chirality. In pharmaceutical manufacturing, the specific 3D arrangement of atoms often determines a drug's efficacy and safety. N-Boc-L-alaninol allows chemists to introduce this specific chirality into complex molecules.

Precursor to Heterocycles: It is frequently used to synthesize chiral heterocycles such as oxazolines, oxazolidinones, and morpholines. These structures are core components in many modern drugs (e.g., antibiotics, antivirals, and kinase inhibitors).

B. Versatile Reactivity (Dual Functional Groups)

Protected Amine: The Boc group protects the amine from unwanted reactions during synthesis but can be easily removed under mild acidic conditions when needed.

Reactive Alcohol: The primary hydroxyl (-OH) group can be transformed into various other functional groups (e.g., halides, azides, esters, or aldehydes) or used to close rings. This dual functionality makes it a flexible "Lego piece" for constructing complex molecular architectures.

C. Role in Peptidomimetics

It is used to create peptidomimetics—molecules that mimic peptides but have better metabolic stability and oral bioavailability. Replacing an amino acid residue with an amino-alcohol derivative (like alaninol) can alter the backbone structure, improving the drug-like properties of the molecule.

D. Agrochemical Applications

Beyond pharma, it serves as an intermediate in the synthesis of chiral pesticides and herbicides, where specific stereoisomers often exhibit higher potency and lower environmental toxicity.

Summary of Specifications (Typical Commercial Grade)

Purity: Usually available in ≥98% or ≥99% purity (HPLC).

Optical Rotation: Specific rotation values (e.g., [α]_D≈-11°)

are guaranteed to ensure enantiomeric excess (ee), which is a critical quality metric for buyers.

Stability: The Boc protection makes the molecule stable for storage and handling compared to the free amine.

In summary, N-Boc-L-alaninol is sold primarily as a high-purity, chiral scaffold that enables medicinal chemists to efficiently build complex, stereo-defined molecules for next-generation therapeutics.